Synthesis of Indenes by a BF3·OEt2-Mediated, One-Pot Reaction of Aryl Homopropargyl Alcohols, Aldehydes, and Arenes

Trimurtulu Kotipalli; Duen Ren Hou

doi:10.1021/acs.orglett.8b01929

Synthesis of Indenes by a BF₃·OEt₂-Mediated, One-Pot Reaction of Aryl Homopropargyl Alcohols, Aldehydes, and Arenes

Trimurtulu Kotipalli, Duen Ren Hou

化學學系

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

21 引文斯高帕斯（Scopus）

摘要

A new and efficient protocol to prepare indenes is reported. Assisted by boron trifluoride diethyl etherate, the one-pot reaction of aryl homopropargyl alcohols and aldehydes in the presence of arenes yielded indene derivatives. The reaction was studied with various substrates, which suggests a cascade reaction including a sequence of Prins, Friedel-Crafts, ring-opening reactions, and Friedel-Crafts to form three C-C bonds leading to indenes.

原文	???core.languages.en_GB???
頁（從 - 到）	4787-4790
頁數	4
期刊	Organic Letters
卷	20
發行號	16
DOIs	https://doi.org/10.1021/acs.orglett.8b01929
出版狀態	已出版 - 17 8月 2018

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10.1021/acs.orglett.8b01929

Brevipolides之合成與製備具有生物活性之新型天然物(3/3)
Hou, D.-R. (PI)
1/08/17 → 30/11/18
研究計畫: Research

CCDC 1847193: Experimental Crystal Structure Determination
Kotipalli, T. (???dataset.roles.dataset.creator???) & Hou, D.-R. (???dataset.roles.dataset.creator???), The Cambridge Structural Database, 2018
DOI: 10.5517/ccdc.csd.cc2004w2, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc2004w2&sid=DataCite
資料集
CCDC 1846842: Experimental Crystal Structure Determination
Kotipalli, T. (???dataset.roles.dataset.creator???) & Hou, D.-R. (???dataset.roles.dataset.creator???), The Cambridge Structural Database, 2018
DOI: 10.5517/ccdc.csd.cc1zzsk9, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1zzsk9&sid=DataCite
資料集

引用此

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abstract = "A new and efficient protocol to prepare indenes is reported. Assisted by boron trifluoride diethyl etherate, the one-pot reaction of aryl homopropargyl alcohols and aldehydes in the presence of arenes yielded indene derivatives. The reaction was studied with various substrates, which suggests a cascade reaction including a sequence of Prins, Friedel-Crafts, ring-opening reactions, and Friedel-Crafts to form three C-C bonds leading to indenes.",

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AU - Kotipalli, Trimurtulu

AU - Hou, Duen Ren

PY - 2018/8/17

Y1 - 2018/8/17

N2 - A new and efficient protocol to prepare indenes is reported. Assisted by boron trifluoride diethyl etherate, the one-pot reaction of aryl homopropargyl alcohols and aldehydes in the presence of arenes yielded indene derivatives. The reaction was studied with various substrates, which suggests a cascade reaction including a sequence of Prins, Friedel-Crafts, ring-opening reactions, and Friedel-Crafts to form three C-C bonds leading to indenes.

AB - A new and efficient protocol to prepare indenes is reported. Assisted by boron trifluoride diethyl etherate, the one-pot reaction of aryl homopropargyl alcohols and aldehydes in the presence of arenes yielded indene derivatives. The reaction was studied with various substrates, which suggests a cascade reaction including a sequence of Prins, Friedel-Crafts, ring-opening reactions, and Friedel-Crafts to form three C-C bonds leading to indenes.

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U2 - 10.1021/acs.orglett.8b01929

DO - 10.1021/acs.orglett.8b01929

M3 - 期刊論文

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AN - SCOPUS:85051710124

SN - 1523-7060

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SP - 4787

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JO - Organic Letters

JF - Organic Letters

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ER -

Synthesis of Indenes by a BF3·OEt2-Mediated, One-Pot Reaction of Aryl Homopropargyl Alcohols, Aldehydes, and Arenes

摘要

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指紋

專案

Brevipolides之合成與製備具有生物活性之新型天然物(3/3)

資料集

CCDC 1847193: Experimental Crystal Structure Determination

CCDC 1846842: Experimental Crystal Structure Determination

引用此

Synthesis of Indenes by a BF₃·OEt₂-Mediated, One-Pot Reaction of Aryl Homopropargyl Alcohols, Aldehydes, and Arenes