每年專案
摘要
Hydrobromination and oxy-isomerization of (o-arylethynyl)benzyl alcohols to yield brominated aryl ketones were achieved with bromotrimethylsilane. The substrate scope suggested that vinyl carbocations, stabilized by the conjugated aryl groups, are the reaction intermediates. 1H-Isochromene was also detected by 1H NMR, and an isolated 1H-isochromene was converted to the product when retreated with TMSBr. The formation of 1H-isochromene is equivalent to a 6-endo-dig cyclization and contrasts with the corresponding reactions under basic conditions, in which the 5-exo-dig process dominated.
原文 | ???core.languages.en_GB??? |
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頁(從 - 到) | 6907-6917 |
頁數 | 11 |
期刊 | Journal of Organic Chemistry |
卷 | 86 |
發行號 | 9 |
DOIs | |
出版狀態 | 已出版 - 7 5月 2021 |
指紋
深入研究「Synthesis of 2-Aryl Acetophenones via Hydrobromination and Oxy-isomerization of (o-Arylethynyl)benzyl Alcohols」主題。共同形成了獨特的指紋。專案
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