TY - JOUR
T1 - Synthesis, bifunctionalization, and remarkable adsorption performance of benzene-bridged periodic mesoporous organosilicas functionalized with high loadings of carboxylic acids
AU - Wu, Hao Yiang
AU - Shieh, Fa Kuen
AU - Kao, Hsien Ming
AU - Chen, Yi Wen
AU - Deka, Juti Rani
AU - Liao, Shih Hsiang
AU - Wu, Kevin C.W.
PY - 2013/5/10
Y1 - 2013/5/10
N2 - Highly ordered benzene-bridged periodic mesoporous organosilicas (PMOs) that were functionalized with exceptionally high loadings of carboxylic acid groups (COOH), up to 80 mol % based on silica, have been synthesized and their use as adsorbents for the adsorption of methylene blue (MB), a basic dye pollutant, and for the loading and release of doxorubicin (DOX), an anticancer drug, is demonstrated. These COOH-functionalized benzene-silicas were synthesized by the co-condensation of 1,4-bis(triethoxysilyl) benzene (BTEB) and carboxyethylsilanetriol sodium salt (CES), an organosilane that contained a carboxylic acid group, in the presence of non-ionic oligomeric surfactant Brij 76 in acidic medium. The materials thus obtained were characterized by a variety of techniques, including powder X-ray diffraction (XRD), nitrogen-adsorption/ desorption isotherms, TEM, and 13C and 29Si solid-state NMR spectroscopy. Owing to the exceptionally high loadings of COOH groups, their high surface areas, and possible π-π-stacking interactions, these adsorbents have very high adsorption capacities and extremely rapid adsorption rates for MB removal and for the controlled loading/release of DOX, thus manifesting their great potential for environmental and biomedical applications.
AB - Highly ordered benzene-bridged periodic mesoporous organosilicas (PMOs) that were functionalized with exceptionally high loadings of carboxylic acid groups (COOH), up to 80 mol % based on silica, have been synthesized and their use as adsorbents for the adsorption of methylene blue (MB), a basic dye pollutant, and for the loading and release of doxorubicin (DOX), an anticancer drug, is demonstrated. These COOH-functionalized benzene-silicas were synthesized by the co-condensation of 1,4-bis(triethoxysilyl) benzene (BTEB) and carboxyethylsilanetriol sodium salt (CES), an organosilane that contained a carboxylic acid group, in the presence of non-ionic oligomeric surfactant Brij 76 in acidic medium. The materials thus obtained were characterized by a variety of techniques, including powder X-ray diffraction (XRD), nitrogen-adsorption/ desorption isotherms, TEM, and 13C and 29Si solid-state NMR spectroscopy. Owing to the exceptionally high loadings of COOH groups, their high surface areas, and possible π-π-stacking interactions, these adsorbents have very high adsorption capacities and extremely rapid adsorption rates for MB removal and for the controlled loading/release of DOX, thus manifesting their great potential for environmental and biomedical applications.
KW - carboxylic acids
KW - doxorubicin
KW - drug delivery
KW - mesoporous materials
KW - methylene blue
UR - http://www.scopus.com/inward/record.url?scp=84877295512&partnerID=8YFLogxK
U2 - 10.1002/chem.201204400
DO - 10.1002/chem.201204400
M3 - 期刊論文
C2 - 23512281
AN - SCOPUS:84877295512
SN - 0947-6539
VL - 19
SP - 6358
EP - 6367
JO - Chemistry - A European Journal
JF - Chemistry - A European Journal
IS - 20
ER -