Studies of the binding mechanism between aptamers and thrombin by circular dichroism, surface plasmon resonance and isothermal titration calorimetry

Keyphrases

• Surface Plasmon Resonance 100%
• Aptamer 100%
• Binding Mechanism 100%
• Isothermal Titration Calorimetry 100%
• Circular Dichroism 100%
• Thrombin 100%
• Binding Site 25%
• Heparin Binding Site 25%
• Fibrinogen Binding 25%
• Electrostatic Interaction 12%
• Thermodynamics 12%
• Specific Interactions 12%
• Ion Effect 12%
• Human Blood 12%
• Non-specific Interaction 12%
• Thrombin Binding Aptamer 12%
• Hydrophobic Effect 12%
• Exosite 12%
• Anticoagulants 12%
• Duplex Structure 12%
• Serine Protease 12%
• G-quadruplex 12%
• Kinetic Discrimination 12%
• G-quadruplex Structure 12%
• Electropositive 12%
• SELEX 12%

Biochemistry, Genetics and Molecular Biology

• Surface Plasmon Resonance 100%
• Circular Dichroism 100%
• Aptamer 100%
• Isothermal Titration Calorimetry 100%
• Thrombin 100%
• Binding Site 44%
• Heparin 22%
• Fibrinogen 22%
• Conformation 11%
• Static Electricity 11%
• Serine Protease 11%
• Exosite 11%