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Sebum free fatty acids enhance the innate immune defense of human sebocytes by upregulating β-defensin-2 expression
Teruaki Nakatsuji
, Mandy C. Kao
, Liangfang Zhang
, Christos C. Zouboulis
, Richard L. Gallo
, Chun Ming Huang
生醫科學與工程學系
研究成果
:
雜誌貢獻
›
期刊論文
›
同行評審
220
引文 斯高帕斯(Scopus)
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深入研究「Sebum free fatty acids enhance the innate immune defense of human sebocytes by upregulating β-defensin-2 expression」主題。共同形成了獨特的指紋。
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Keyphrases
Sebocytes
100%
Defensin
100%
Free Fatty Acids
100%
Sebum
100%
Innate Immune Defense
100%
HBD-2
81%
Cluster of Differentiation 36 (CD36)
27%
Cutibacterium Acnes (C. acnes)
18%
Oleic Acid
18%
Supernatant
18%
NF-B
18%
Acid Activation
18%
Antibacterial Activity
18%
Sebaceous Gland
18%
Antimicrobial Activity
18%
Vehicle Control
9%
Signaling Pathway
9%
Western Blotting
9%
Palmitic Acid
9%
Antimicrobial Peptides
9%
Transactivation
9%
Incubation
9%
Antimicrobial Therapy
9%
Highly Selective
9%
Gram-positive Bacteria
9%
Hair Follicle
9%
Orthologs
9%
Mouse Ear
9%
Acne Vulgaris Treatment
9%
Lauric Acid
9%
Skin Surface
9%
Epicutaneous
9%
Ear Skin
9%
Enhanced Antimicrobial Activity
9%
Human Cathelicidin LL-37
9%
HBD-1
9%
Free Fatty Acids Uptake
9%
Human Defensins
9%
Selective Inhibitor
9%
BMS-345541
9%
Antibacterial Defense
9%
HBD-3
9%
Fatty Acid Translocase
9%
Immunology and Microbiology
Sebum
100%
Antimicrobial Activity
75%
Antimicrobial Agent
75%
CD36
50%
Antibacterial Activity
50%
Propionibacterium acnes
50%
Upregulation
50%
Supernatant
50%
Sebaceous Gland
50%
Western Blot
25%
Antimicrobial Peptides
25%
Gram-Positive Bacteria
25%
Hair Follicle
25%
Orthology
25%
Skin Surface
25%
Transactivation
25%
CD36 Antigen
25%
Cluster of Differentiation
25%
Fatty Acid Transport
25%
Cathelicidin
25%
Medicine and Dentistry
Fatty Acid
100%
Sebum
100%
Antimicrobial Activity
25%
Antimicrobial Agent
25%
Propionibacterium acnes
16%
Upregulation
16%
Oleic Acid
16%
Sebaceous Gland
16%
Antibacterial Activity
16%
Acne Vulgaris
8%
Western Blot
8%
Antiinfective Agent
8%
Phosphotransferase
8%
Hair Follicle
8%
Cell Signaling Pathway
8%
Antimicrobial Therapy
8%
Incubation
8%
Lauric Acid
8%
Gram-Positive Bacteria
8%
Adenosine Phosphate
8%
Skin Surface
8%
Cathelicidin Antimicrobial Peptide LL 37
8%
CD36 Antigen
8%
Fatty Acid Transport
8%
Orthology
8%
Transactivation
8%
Polypeptide Antibiotic Agent
8%
Palmitic Acid
8%
Pharmacology, Toxicology and Pharmaceutical Science
Fatty Acid
100%
Antimicrobial Agent
25%
Propionibacterium acnes
16%
Antibacterial Activity
16%
Oleic Acid
16%
Acne Vulgaris
8%
Western Blot
8%
Polypeptide Antibiotic Agent
8%
Phosphotransferase
8%
Antiinfective Agent
8%
Gram Positive Bacterium
8%
Lauric Acid
8%
Antimicrobial Therapy
8%
Adenosine Phosphate
8%
Palmitic Acid
8%
CD36 Antigen
8%
Cathelicidin Antimicrobial Peptide LL 37
8%