Real-time monitoring DNA hybridization by guided resonant mode biosensor

Jiann Hwa Lue, Ting Jou Ding, Tsung Hsun Yang, Hsin Chun Huang, Che Lung Hsu, Jen Tsai Liu, Wen Yih Chen, Jenq Yang Chang

研究成果: 書貢獻/報告類型會議論文篇章同行評審

2 引文 斯高帕斯(Scopus)

摘要

In this paper, a label free approach of the DNA hybridization detection by the guided-mode resonance (GMR) spectroscopy sensor is presented. The GMR biosensor can easily detect any slight variation of the DNA hybridization by the resonant wavelength peak shift. The corresponding peak wavelength shifts of the capture DNA, the target DNA and the probe DNA serially hybridized reactions from GMR are measured, respectively. Furthermore, the stability and reliability of the GMR biosensor for nucleic acid hybridization have also been examined. The result obviously reveals the feasibility of implementation of the GMR-based DNA microarray for detecting on the dynamics of DNA hybridization.

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主出版物標題NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems
頁面1208-1211
頁數4
DOIs
出版狀態已出版 - 2011
事件6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011 - Kaohsiung, Taiwan
持續時間: 20 2月 201123 2月 2011

出版系列

名字NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems

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???event.eventtypes.event.conference???6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011
國家/地區Taiwan
城市Kaohsiung
期間20/02/1123/02/11

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