Quantitative measurement of γ-secretase-mediated amyloid precursor protein and notch cleavage in cell-based luciferase reporter assay platforms

Keyphrases

• Cell-based 100%
• Quantitative Measurement 100%
• Luciferase Reporter Assay 100%
• Amyloid Precursor Protein 100%
• Secretase 100%
• Protein Cleavage 100%
• Notch Cleavage 100%
• Assay Platform 100%
• APP-C99 50%
• Gal4 33%
• Gal4-VP16 33%
• Differential Response 16%
• Drug Discovery 16%
• HEK293 Cells 16%
• C-terminal Fragments 16%
• Reporter Gene Assay 16%
• Cellular Context 16%
• Luciferase Reporter System 16%
• Firefly Luciferase 16%
• ErbB Inhibitor 16%
• Luciferase Reporter Gene 16%
• New Assay 16%
• AD Therapy 16%
• Reporter Assay 16%
• Secretase Activity 16%

Biochemistry, Genetics and Molecular Biology

• Luciferase 100%
• Secretase 100%
• Notch 100%
• Amyloid Precursor Protein 100%
• Quantitative Technique 100%
• Reporter Gene 28%
• C-Terminus 14%
• Promoter Region 14%

Neuroscience

• Secretase 100%
• Amyloid Precursor Protein 100%
• Notch 100%
• Luciferase 100%
• Reporter Gene 28%
• C-Terminus 14%
• Promoter Region 14%
• Firefly Luciferase 14%