Preparation and hemocompatibility of surface-modified membranes

Akira Takahashi; Ryoji Umehara; Yuki Matsuoka; Satsuki Egashira; Shizue Natori; Akon Higuchi

Preparation and hemocompatibility of surface-modified membranes

Akira Takahashi, Ryoji Umehara, Yuki Matsuoka, Satsuki Egashira, Shizue Natori, Akon Higuchi

化學工程與材料工程學系

研究成果: 會議貢獻類型 › 會議論文 › 同行評審

摘要

When blood is applied to biomaterials, there is an initial adsorption of serum proteins. This is followed by platelet adhesion and activation of coagulation pathways, leading to thrombus formation. Several surface-modified polysulfone (PSf) hollow fibers were prepared with chemical modification. In this study, the polymerization of vinylpyrrolidone (VP) acryl morpholine (ACMO), N,N'-dimethyl acylamide(DMAA) and zwitterionic monomer of N,N-dimethyl-N- methacryloxyethyl-N-(3-sulfopropyl)ammonium betaine (SPE) on the surface of the polysulfone hollow fibers is reported. Platelet adhesion and serum protein adsorption on the polysulfone membranes conjugated with SPE, VP, ACMO and DMAA polymer on the surface from human plasma are investigated.

原文	???core.languages.en_GB???
頁面	1838
頁數	1
出版狀態	已出版 - 2006
事件	55th SPSJ Annual Meeting - Nagoya, Japan 持續時間: 24 5月 2006 → 26 5月 2006

???event.eventtypes.event.conference???

???event.eventtypes.event.conference???	55th SPSJ Annual Meeting
國家/地區	Japan
城市	Nagoya
期間	24/05/06 → 26/05/06

引用此

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abstract = "When blood is applied to biomaterials, there is an initial adsorption of serum proteins. This is followed by platelet adhesion and activation of coagulation pathways, leading to thrombus formation. Several surface-modified polysulfone (PSf) hollow fibers were prepared with chemical modification. In this study, the polymerization of vinylpyrrolidone (VP) acryl morpholine (ACMO), N,N'-dimethyl acylamide(DMAA) and zwitterionic monomer of N,N-dimethyl-N- methacryloxyethyl-N-(3-sulfopropyl)ammonium betaine (SPE) on the surface of the polysulfone hollow fibers is reported. Platelet adhesion and serum protein adsorption on the polysulfone membranes conjugated with SPE, VP, ACMO and DMAA polymer on the surface from human plasma are investigated.",

keywords = "Hemocompatibility, Hollow fiber, Polysultone, Zwitter ion",

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TY - CONF

T1 - Preparation and hemocompatibility of surface-modified membranes

AU - Takahashi, Akira

AU - Umehara, Ryoji

AU - Matsuoka, Yuki

AU - Egashira, Satsuki

AU - Natori, Shizue

AU - Higuchi, Akon

PY - 2006

Y1 - 2006

N2 - When blood is applied to biomaterials, there is an initial adsorption of serum proteins. This is followed by platelet adhesion and activation of coagulation pathways, leading to thrombus formation. Several surface-modified polysulfone (PSf) hollow fibers were prepared with chemical modification. In this study, the polymerization of vinylpyrrolidone (VP) acryl morpholine (ACMO), N,N'-dimethyl acylamide(DMAA) and zwitterionic monomer of N,N-dimethyl-N- methacryloxyethyl-N-(3-sulfopropyl)ammonium betaine (SPE) on the surface of the polysulfone hollow fibers is reported. Platelet adhesion and serum protein adsorption on the polysulfone membranes conjugated with SPE, VP, ACMO and DMAA polymer on the surface from human plasma are investigated.

AB - When blood is applied to biomaterials, there is an initial adsorption of serum proteins. This is followed by platelet adhesion and activation of coagulation pathways, leading to thrombus formation. Several surface-modified polysulfone (PSf) hollow fibers were prepared with chemical modification. In this study, the polymerization of vinylpyrrolidone (VP) acryl morpholine (ACMO), N,N'-dimethyl acylamide(DMAA) and zwitterionic monomer of N,N-dimethyl-N- methacryloxyethyl-N-(3-sulfopropyl)ammonium betaine (SPE) on the surface of the polysulfone hollow fibers is reported. Platelet adhesion and serum protein adsorption on the polysulfone membranes conjugated with SPE, VP, ACMO and DMAA polymer on the surface from human plasma are investigated.

KW - Hemocompatibility

KW - Hollow fiber

KW - Polysultone

KW - Zwitter ion

UR - http://www.scopus.com/inward/record.url?scp=33749823808&partnerID=8YFLogxK

M3 - 會議論文

AN - SCOPUS:33749823808

SP - 1838

T2 - 55th SPSJ Annual Meeting

Y2 - 24 May 2006 through 26 May 2006

ER -

Preparation and hemocompatibility of surface-modified membranes

摘要

???event.eventtypes.event.conference???

指紋

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