Polymeric nanopillar arrays for cell traction force measurements

Chiung Wen Kuo, Jau Ye Shiu, Fan Ching Chien, Shih Min Tsai, Di Yan Chueh, Peilin Chen

研究成果: 雜誌貢獻期刊論文同行評審

32 引文 斯高帕斯(Scopus)

摘要

This paper reports the development of a novel force measurement device based on polymeric nanopillar arrays. The device was fabricated by a process combining nanosphere lithography, oxygen plasma treatment, deep etching and nano-molding. Well-ordered polymeric nanopillar arrays with various diameters and aspect ratios were fabricated and used as cell culture substrates. Cell traction forces were measured by the deflection of the nanopillars. Since the location of the nanopillars can be monitored at all times, this device allows for the measurement of the evolution of adhesion forces over time.

原文???core.languages.en_GB???
頁(從 - 到)3152-3158
頁數7
期刊Electrophoresis
31
發行號18
DOIs
出版狀態已出版 - 9月 2010

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