Particle Size and Crystal Habit Modification of Active Pharmaceutical Ingredient Using Cooling Sonocrystallization: A Case Study of Probenecid

Chemical Compounds

• Cooling 57%
• Crystal Habit 83%
• Crystal Morphology 16%
• Ethanol 21%
• Fourier Transform Infrared Spectroscopy 9%
• Modification 36%
• Organic Solvent 11%
• Pharmaceutical 47%
• Probenecid 100%
• Reaction Yield 6%
• Size Distribution 14%
• Solubility 20%
• Solvent 30%
• Sonication 33%
• X-Ray 9%

Engineering & Materials Science

• Cooling 45%
• Crystals 64%
• Diffractometers 14%
• Drug products 71%
• Ethanol 21%
• Experiments 3%
• Fourier transform infrared spectroscopy 13%
• Organic solvents 15%
• Particle size 61%
• Powders 8%
• Recovery 7%
• Solubility 23%
• Sonication 32%
• Throughput 7%
• Ultrasonics 9%
• X rays 9%

Physics & Astronomy

• cooling 44%
• crystals 31%
• diffractometers 11%
• ethyl alcohol 21%
• habits 79%
• infrared spectroscopy 9%
• ingredients 67%
• recovery 8%
• solubility 19%
• trucks 11%
• x rays 4%