TY - JOUR
T1 - Noncontact radio-frequency ablation for obtaining deeper lesions
AU - Zhang, Jie
AU - Tsai, Jang Zern
AU - Cao, Hong
AU - Chen, Yi
AU - Will, James A.
AU - Vorperian, Vicken R.
AU - Webster, John G.
N1 - Funding Information:
Manuscript received April 25, 2002; revised October 12, 2002. This work was supported by the National Institutes of Health (NIH) under Grant HL56143. Asterisk indicates corresponding author. J. Zhang is with the Department of Electrical and Computer Engineering, University of Wisconsin-Madison, Madison, WI 53706 USA. J.-Z. Tsai is with the Department of Electrical Engineering, National Central University, Jung-Li, Taoyuan 32054, Taiwan. H. Cao is with St. Jude Medical - Daig Division, Minnetonka, MN 55345 USA Y. Chen is with the Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI 53706 USA. J. A. Will is with the Department of Animal Health and Biomedical Sciences, University of Wisconsin-Madison, Madison, WI 53706 USA. V. R. Vorperian is with the Department of Medicine, University of Wisconsin-Madison, Madison, WI 53792 USA. *J. G. Webster is with the Department of Biomedical Engineering, University of Wisconsin-Madison, 1550 Engineering Drive, Madison, WI 53706 USA (e-mail: Webster@engr.wisc.edu). Digital Object Identifier 10.1109/TBME.2002.807647
PY - 2003/2/1
Y1 - 2003/2/1
N2 - Radio-frequency (RF) cardiac catheter ablation has been very successful for treating some cardiac arrhythmias, however, the success rate for ventricular tachycardias is still not satisfactory. Some existing methods for developing deeper lesions include active cooling of the electrode and modifying the electrode shape. We propose a method of noncontact ablation, to solve this problem. We apply 120 W of power through an 8-mm electrode for a 120-s duration, with distances from 0 to 3 mm between electrode and myocardium, to create lesions in myocardium. We apply flow rates of 1, 3, and 5 L/min to determine their effect. Results show that with an optimal distance from 0.5 to 1.5 mm between electrode and myocardium, we increase lesion depth from 7.5 mm for contact ablation to 9.5 mm for noncontact ablation. For different flow rates, the optimal distance various. The effect of flow rate is not obvious. Higher flow rate does not lead to a deeper lesion.
AB - Radio-frequency (RF) cardiac catheter ablation has been very successful for treating some cardiac arrhythmias, however, the success rate for ventricular tachycardias is still not satisfactory. Some existing methods for developing deeper lesions include active cooling of the electrode and modifying the electrode shape. We propose a method of noncontact ablation, to solve this problem. We apply 120 W of power through an 8-mm electrode for a 120-s duration, with distances from 0 to 3 mm between electrode and myocardium, to create lesions in myocardium. We apply flow rates of 1, 3, and 5 L/min to determine their effect. Results show that with an optimal distance from 0.5 to 1.5 mm between electrode and myocardium, we increase lesion depth from 7.5 mm for contact ablation to 9.5 mm for noncontact ablation. For different flow rates, the optimal distance various. The effect of flow rate is not obvious. Higher flow rate does not lead to a deeper lesion.
KW - Ablation
KW - Electrode
KW - Noncontact electrode
KW - Radio-frequency ablation
UR - http://www.scopus.com/inward/record.url?scp=0037296196&partnerID=8YFLogxK
U2 - 10.1109/TBME.2002.807647
DO - 10.1109/TBME.2002.807647
M3 - 期刊論文
C2 - 12665035
AN - SCOPUS:0037296196
SN - 0018-9294
VL - 50
SP - 218
EP - 223
JO - IEEE Transactions on Biomedical Engineering
JF - IEEE Transactions on Biomedical Engineering
IS - 2
ER -