Nasopharyngeal cancer cell death induced by high-dose gold nanoparticles

Ming Ying Lan, Yen Bin Hsu, Jin Ching Lin, Ching Yin Ho, Sheng Wei Lee

研究成果: 書貢獻/報告類型會議論文篇章同行評審

摘要

This study investigated if gold nanoparticles (AuNPs) could be used as a new therapeutic agent for NPC by evaluating their anti-tumor effect in vitro. AuNPs prepared in this study had an average diameter of 20.5 nm and they were observed under light microscopy as dark material aggregated in the cells after treatment. The AuNPs reduced cell viability in a concentration-dependant manner by Trypan Blue assay: 74.7% at 50 μM, 39.0% at 100μM, and 7.1% at 200 μM, respectively. TUNEL stain was positive in AuNP-treated cells. The AuNP possess specific imaging properties and is cytotoxic to NPC cells at high concentrations.

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主出版物標題4th IEEE International NanoElectronics Conference, INEC 2011
DOIs
出版狀態已出版 - 2011
事件4th IEEE International Nanoelectronics Conference, INEC 2011 - Tao-Yuan, Taiwan
持續時間: 21 6月 201124 6月 2011

出版系列

名字Proceedings - International NanoElectronics Conference, INEC
ISSN(列印)2159-3523

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???event.eventtypes.event.conference???4th IEEE International Nanoelectronics Conference, INEC 2011
國家/地區Taiwan
城市Tao-Yuan
期間21/06/1124/06/11

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