Nanostructured silicon coupled with iron oxide magnetic nanoparticles as enhanced desorption/ionization on silicon mass spectrometry for phosphopeptide analysis

C. W. Tsao, W. Y. Chen, C. H. Lin, Y. C. Cheng

研究成果: 書貢獻/報告類型會議論文篇章同行評審

摘要

In this paper, we demonstrate using nanostructured silicon (nSi) as desorption/ionization on silicon (DIOS) substrate and coupled with functionalized ioron oxide magnetic nanoparticles (MNPs) for phosphopeptide mass spectrometry (MS) analysis. Phospholyted peptide has been successfully selectively detected by nSi incorporated with TiO2 and ZnO MNPs. Results show that MNPs coupled nSi MS technique (MNPs/nSi-MS) is a high performance approach for phosphopeptide analysis where nSi service as DIOS-MS target substrate for high sensitivity MS detection and MNPs can selectively capture the phosphopeptide for enhanced MS detection selectivity.

原文???core.languages.en_GB???
主出版物標題NSTI
主出版物子標題Advanced Materials - TechConnect Briefs 2015
編輯Bart Romanowicz, Matthew Laudon
發行者Taylor and Francis Inc.
頁面34-38
頁數5
ISBN(電子)9781498747271
出版狀態已出版 - 2015
事件10th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 18th Annual Nanotech Conference and Expo, and the 2015 National SBIR/STTR Conference - Washington, United States
持續時間: 14 6月 201517 6月 2015

出版系列

名字NSTI: Advanced Materials - TechConnect Briefs 2015
1

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???event.eventtypes.event.conference???10th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 18th Annual Nanotech Conference and Expo, and the 2015 National SBIR/STTR Conference
國家/地區United States
城市Washington
期間14/06/1517/06/15

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