Multiscale entropy analysis of pulse wave velocity for assessing atherosclerosis in the aged and diabetic

Hsien Tsai Wu, Po Chun Hsu, Cheng Feng Lin, Hou Jun Wang, Cheuk Kwan Sun, An Bang Liu, Men Tzung Lo, Chieh Ju Tang

研究成果: 雜誌貢獻期刊論文同行評審

46 引文 斯高帕斯(Scopus)

摘要

This study proposed a dynamic pulse wave velocity (PWV)-based biomedical parameter in assessing the degree of atherosclerosis for the aged and diabetic populations. Totally, 91 subjects were recruited from a single medical institution between July 2009 and October 2010. The subjects were divided into four groups: young healthy adults (Group 1, n 22), healthy upper middle-aged adults (Group 2, n 28), type 2 diabetics with satisfactory blood sugar control (Group 3, n 21), and unsatisfactory blood sugar control (Group 4, n 20). A self-developed six-channel electrocardiography (ECG)-PWV-based equipment was used to acquire 1000 successive recordings of PWV foot values within 30 min. The data, thus, obtained were analyzed with multiscale entropy (MSE). Large-scale MSE index (MEI LS) was chosen as the assessment parameter. Not only did MEI LS successfully differentiate between subjects in Groups 1 and 2, but it also showed a significant difference between Groups 3 and 4. Compared with the conventional parameter of PWV foot and MEI on R-R interval i.e., MEI (RRI) in evaluating the degree of atherosclerotic change, the dynamic parameter, MEI LS (PWV), could better reflect the impact of age and blood sugar control on the progression of atherosclerosis.

原文???core.languages.en_GB???
文章編號5893923
頁(從 - 到)2978-2981
頁數4
期刊IEEE Transactions on Biomedical Engineering
58
發行號10 PART 2
DOIs
出版狀態已出版 - 10月 2011

指紋

深入研究「Multiscale entropy analysis of pulse wave velocity for assessing atherosclerosis in the aged and diabetic」主題。共同形成了獨特的指紋。

引用此