Kinetics and morphology analysis for fabrication a mimetic bio-membrane on Brij-76 derived surface

Liang Yu Chen, Jia Jia Lin, Ming Shen Lin, Shiu Mei Chiu, Yung Chang, Wen Yih Chen

研究成果: 雜誌貢獻期刊論文同行評審

3 引文 斯高帕斯(Scopus)

摘要

We investigated the effects of the phosphoglycerides (l-α-dipalmitoyl-phosphatidylcholine (DPPC) and lecithin (egg PC)) and cholesterol contents of liposome on the topographies and the kinetics deposition mechanisms on the polyethylene glycol ocatadecyl ether (Brij-76) derived solid surface by (1) the morphology analysis of atomic force microscopy and (2) the real-time monitoring of quartz crystal microbalance sensor. The DPPC-LUVs depositions were the major vesicular lipid bilayer on the surface, while the deposited egg PC-LUVs formed the planar lipid bilayer. The roles of phosphoglycerides and the cholesterol contents in the mechanism and the conformation of lipid vesicles onto the surface were discussed.

原文???core.languages.en_GB???
頁(從 - 到)86-91
頁數6
期刊Colloids and Surfaces A: Physicochemical and Engineering Aspects
296
發行號1-3
DOIs
出版狀態已出版 - 15 3月 2007

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