Transient ionospheric disturbances in the total electron content (TEC) are examined before and after the M9.0 2011 off the Pacific coast of Tohoku Earthquake to find ionospheric responses to the radiation caused by Fukushima I nuclear power plant accident, which was damaged by the earthquake and tsunamis. The TEC is derived from records of a ground-based receiving network of GPS Earth Observation Network (GEONET) in Japan. Both small enhancement and disturbance of TEC were detected over the nuclear power plant after the radiation was suddenly enhanced on March 14 of 2011, while similar signatures were not detected in the other sudden radiation enhancements. Further, no continuous enhancement and disturbance lasting for more than an hour were observed over the nuclear power plant. Therefore, the results indicate that radioactive materials may not cause the ionospheric disturbance or disturb the ionosphere in highly specific circumstance even if such effects exist.