We report measurements from the CLEO detector of the rate of Ξ and Λ production in e+e- interactions in the upsilon region. Hyperon production from the decay of the (1s) is compared with continuum e+e- data. The ratio of the production rates of Λ (and Λ - ) to K0 (and K - 0) on the (1s) is 0.21 ± 0.03, much larger than in the continuum, 0.07 ± 0.01. The ratios of the production rates of the Ξ and Λ are comparable, 0.10±0.02[(1S)] and 0.07 ± 0.02 (continuum). We discuss some implications of the data for gluon and quark fragmentation models.