Graptopetalum Paraguayense Ameliorates Chemical-Induced Rat Hepatic Fibrosis In Vivo and Inactivates Stellate Cells and Kupffer Cells In Vitro

Agriculture & Biology

• Graptopetalum paraguayense 100%
• liver cirrhosis 71%
• Kupffer cells 70%
• liver 29%
• extracts 26%
• rats 26%
• fibrosis 20%
• cells 15%
• hepatoprotective effect 14%
• oral administration 11%
• inflammation 10%
• therapeutics 8%
• tumor necrosis factors 7%
• prothrombin 7%
• carbon tetrachloride 7%
• interleukin-10 6%
• hydroxyproline 6%
• herbal medicines 6%
• bilirubin 6%
• interleukin-6 6%
• alanine transaminase 5%
• immunohistochemistry 5%
• aspartate transaminase 5%
• Taiwan 5%
• smooth muscle 5%
• lipopolysaccharides 5%
• cytokines 5%
• actin 5%
• cell death 5%
• nitric oxide 4%
• collagen 4%
• Western blotting 4%
• toxins 4%
• assays 2%
• methodology 1%

Medicine & Life Sciences

• Kupffer Cells 60%
• Fibrosis 37%
• Hepatic Stellate Cells 35%
• Liver 25%
• In Vitro Techniques 22%
• Dimethylnitrosamine 20%
• Liver Cirrhosis 13%
• Oral Administration 12%
• Carbon Tetrachloride 8%
• Inflammation 8%
• Prothrombin 8%
• Hydroxyproline 8%
• Herbal Medicine 8%
• Traditional Medicine 7%
• Aspartate Aminotransferases 7%
• Taiwan 7%
• Bilirubin 7%
• Alanine Transaminase 7%
• Interleukin-10 6%
• Smooth Muscle 6%
• Lipopolysaccharides 6%
• Actins 6%
• Cultured Cells 6%
• Nitric Oxide 5%
• Interleukin-6 5%
• Collagen 5%
• Cell Death 5%
• Tumor Necrosis Factor-alpha 5%
• Immunohistochemistry 4%
• Western Blotting 4%
• Cytokines 4%
• Mortality 3%
• Wounds and Injuries 3%
• Therapeutics 2%

Chemical Compounds

• Stellate Crystal 81%
• Hepatoprotective 35%
• Antifibrotic 21%
• Hydroxyproline 16%
• Prothrombin 16%
• Bilirubin 14%
• Apoptotic 14%
• Aspartate 13%
• Cell Death 13%
• Alanine 12%
• Nitric Oxide 11%
• Collagen 11%
• Marker 11%