Genetic association of blaSHV-5 with transposable elements IS26 and IS5 in Klebsiella pneumoniae from Taiwan

W. L. Yu, S. C. Chen, S. W. Hung, Y. C. Chuang, J. G. Chung, I. C. Chen, L. T. Wu

研究成果: 雜誌貢獻期刊論文同行評審

9 引文 斯高帕斯(Scopus)

摘要

A cloned 5248-bp EcoRI fragment from the Klebsiella pneumoniae transferable plasmid pKP53 (> 70 kb) containing blaSHV-5 was sequenced. Insertion sequences IS26 and IS5 were found downstream from blaSHV-5. The DNA sequences of the genetic environment surrounding blaSHV-5 were homologous to plasmid p1658/97 from Escherichia coli, containing a truncated recF gene and a truncated deoR gene upstream and downstream from blaSHV-5, respectively. RecF may be involved in blaSHV-5 translocation to the plasmid by RecF-dependent recombination. This novel genetic environment may be associated with the successful proliferation and/or expression of SHV-5 in K. pneumoniae strains from Taiwan.

原文???core.languages.en_GB???
頁(從 - 到)806-809
頁數4
期刊Clinical Microbiology and Infection
12
發行號8
DOIs
出版狀態已出版 - 8月 2006

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