Frequency analysis and application of a buckypaper-based bionanosensor

A novel bionanosensor (BNS) with multi-walled carbon nanotubes for the precise detection of DNA-hybridization was developed earlier using intermediate frequency electrical measurements. In the earlier project also a modeling technique for detailed understanding of the DNA-hybridization taking place on the surface of a sensor was also developed. In the current project, the authors have advanced the BNS fabrication using buckypaper for highly efficient detection of DNA-hybridization with controlled device resistance. Buckypaper is a thin sheet of an aggregate of carbon nanotubes (CNTs). Furthermore, the modeling of these sensors using pole-zero plots in the z-plane suggests the orientation of CNTs within the buckypaper in the presence of hybridized-DNA in the high frequency range (12-16 MHz). This modeling technique is not limited only to the BNS under study but significantly increases our knowledge on CNT-DNA interaction. Thus, this research yields successful application of buckypaper as a BNSs and strongly suggests the possible orientation of CNTs within buckypaper using hybridized-DNA at a high frequency range.