Fractal Dimension Analysis for Quantifying Brain Atrophy of Multiple System Atrophy of the Cerebellar Type (MSA-C)

Z. Y. Wang, B. W. Soong, P. S. Wang, C. W. Jao, K. K. Shyu, Y. T. Wu

研究成果: 書貢獻/報告類型會議論文篇章同行評審

摘要

Multiple system atrophy-cerebellar (MSA-C) is a degenerative neurological disease of brain. In this study, we used three-dimensional (3D) fractal dimension (FD) method to investigate the structural complexity change of human cerebellum white matter (CBWM) and gray matter (CBGM) for MSA-C disease diagnosis. Twenty patients and twenty-three normal subjects as the control group participated in this study. The T-1 weighted magnetic resonance (MR) images were processed and 3D CBGM and 3D CBGM were analyzed by the FD method. Results demonstrated that the FD values of patients' CBWM and CBGM decreased significantly, and that their CBWM FD values decreased more significant than that of CBGM. Results also showed that the 3D FD method was superior to the conventional volumetric method in terms of better reliability, accuracy, and sensitivity.

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主出版物標題13th International Conference on Biomedical Engineering - ICBME 2008
頁面730-733
頁數4
DOIs
出版狀態已出版 - 2009
事件13th International Conference on Biomedical Engineering, ICBME 2008 - , Singapore
持續時間: 3 12月 20086 12月 2008

出版系列

名字IFMBE Proceedings
23
ISSN(列印)1680-0737

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???event.eventtypes.event.conference???13th International Conference on Biomedical Engineering, ICBME 2008
國家/地區Singapore
期間3/12/086/12/08

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