Enantioselective synthesis of (+)-brevipolide H

Ching Nung Chen, Duen Ren Hou

研究成果: 雜誌貢獻期刊論文同行評審

8 引文 斯高帕斯(Scopus)

摘要

The enantioselective synthesis of natural brevipolide H is reported for the first time. By way of Sharpless epoxidation of penta-1,4-dien-3-ol, both enantiomerically pure epoxides were converted to the corresponding olefins for cross metathesis. Subsequent transformations, including epoxide ring opening, esterifications, cyclopropanation, oxidation and ring-closing metathesis, provided the target molecule. This synthesis successfully addresses previous shortcomings in preparing brevipolides.

原文???core.languages.en_GB???
頁(從 - 到)6762-6768
頁數7
期刊Organic and Biomolecular Chemistry
14
發行號28
DOIs
出版狀態已出版 - 2016

指紋

深入研究「Enantioselective synthesis of (+)-brevipolide H」主題。共同形成了獨特的指紋。

引用此