Drug-carrier screening on a chip

Tu Lee, Jia Lee

研究成果: 雜誌貢獻回顧評介論文同行評審

7 引文 斯高帕斯(Scopus)

摘要

In this article, the authors discuss the development of a rapid screening technology based on the integration of spin-on and optical microscopy. This method was tested on four solid dispersion systems, and the spin-on films of each of these systems with various drug-carrier ratios at 25°C were examined by optical microscopy. The results of these experiments showed that drug-carrier screening on a chip had a fast solvent-removal rate by spinning (3-10 s) and a short image-acquisition time by optical microscopy (1-2 min), thereby proving this approach to be suitable for the accelerated development of new solid dispersion materials.

原文???core.languages.en_GB???
頁(從 - 到)40-48
頁數9
期刊Pharmaceutical Technology North America
27
發行號1
出版狀態已出版 - 1 1月 2003

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