Discovering common structural motifs from SSU 16 S ribosomal RNA secondary structures

Hsien Da Huang, Shu Fen Fang, Jorng Tzong Horng, Cheng Yan Kao

研究成果: 書貢獻/報告類型會議論文篇章同行評審

摘要

Some structural motifs, like tetra-loops, in ribosomal RNA are known to functionally implicate in virtually every aspect of protein synthesis. Our aim in this study is to discover common structural motifs (CSMs), which are related to specific domains or functions, within the secondary structures of ribosomal RNAs in a data set constructed. After applying data mining techniques to mine the common structural motifs, a machine learning approach is used to find significant discriminating common structural motifs from groups of organisms. By applying to several data sets constructed in this study, it suggests that the CSMs can provide effective information to classify organisms and help biologists understand the functions of ribosomal RNA. From the experiments of the classification of organisms and the construction of phylogenetic trees by CSMs mined, we find our approach is promising.

原文???core.languages.en_GB???
主出版物標題Proceedings - 2nd Annual IEEE International Symposium on Bioinformatics and Bioengineering, BIBE 2001
發行者Institute of Electrical and Electronics Engineers Inc.
頁面104-111
頁數8
ISBN(電子)0769514235, 9780769514239
DOIs
出版狀態已出版 - 2001
事件2nd Annual IEEE International Symposium on Bioinformatics and Bioengineering, BIBE 2001 - Bethesda, United States
持續時間: 4 11月 20016 11月 2001

出版系列

名字Proceedings - 2nd Annual IEEE International Symposium on Bioinformatics and Bioengineering, BIBE 2001

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???event.eventtypes.event.conference???2nd Annual IEEE International Symposium on Bioinformatics and Bioengineering, BIBE 2001
國家/地區United States
城市Bethesda
期間4/11/016/11/01

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