Coupled waveguide-surface plasmon resonance biosensors constructed with sub-wavelength grating

F. C. Chien, J. N. Yih, C. Y. Lin, K. L. Lee, Y. M. Chu, Y. C. Mao, W. H. Wang, P. K. Wei, S. J. Chen

研究成果: 書貢獻/報告類型會議論文篇章同行評審

1 引文 斯高帕斯(Scopus)


A coupled waveguide-surface plasmon resonance (CWSPR) biosensor constructed with sub-wavelength grating structure is developed and used to analyze biomolecular interaction in real time. The normal incident white light is coupled into the waveguide layer through the sub-wavelength grating, and hence it has an enhanced wave vector to excite the localized surface plasmons on the metal grating surface. The CWSPR biosensor with the surface plasmon resonance (SPR) mode and the waveguide mode not only retains the same sensing sensitivity as that of a conventional SPR device, but also yields sharper dips in the reflectivity spectrum and therefore provides an improved measurement precision. Moreover, without the limitation of a conventional attenuated total reflection coupler and with the help of normal incidence, the system is more flexible and feasible for protein microarray and imaging applications.

主出版物標題Nanobiophotonics and Biomedical Applications III
出版狀態已出版 - 2006
事件Nanobiophotonics and Biomedical Applications III - San Jose, CA, United States
持續時間: 23 1月 200624 1月 2006


名字Progress in Biomedical Optics and Imaging - Proceedings of SPIE


???event.eventtypes.event.conference???Nanobiophotonics and Biomedical Applications III
國家/地區United States
城市San Jose, CA


深入研究「Coupled waveguide-surface plasmon resonance biosensors constructed with sub-wavelength grating」主題。共同形成了獨特的指紋。