摘要
In the current studies, we investigated the use of immobilized DNA membranes for chiral separation. D-Phenylalanine preferentially permeated through immobilized DNA membranes with a pore size <2.0nm (molecular weight cut-off (MWCO)<5000) while L-phenylalanine preferentially permeated through immobilized DNA membranes with a pore size >2.0nm (MWCO>5000). The pore size of the immobilized DNA membranes regulated preferential permeation of the enantiomer through the membranes. The immobilized DNA membranes are categorized as channel-type membranes and not as affinity membranes. We further propose a multi-stage cascade for chiral separation by ultrafiltration. When the two types of the membranes were used in a cascade filtration system, there was no change of concentration ratio between L-enantiomer and D-enantiomer in the feed solution at each stage. Only two membranes were necessary in a multi-stage processes if both membrane types were used.
原文 | ???core.languages.en_GB??? |
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頁(從 - 到) | 207-218 |
頁數 | 12 |
期刊 | Journal of Membrane Science |
卷 | 221 |
發行號 | 1-2 |
DOIs | |
出版狀態 | 已出版 - 15 8月 2003 |