摘要
Bromotrimethylsilane-promoted benzannulation of o-alkynylbenzaldehydes and alkynes to yield 1-naphthyl aryl ketones is reported. The reaction conditions are mild, metal-free, and do not require pretreatment/protection of the substrates. We found that aryl propargyl alcohols were very effective substrates for this reaction, compared with other alkynes. Studies on the reaction scope, monitoring the reaction progress by 1H NMR, and theoretical calculations suggest that isochromenylium (benzopyrilium) ion is the key reaction intermediate. (Figure presented.).
原文 | ???core.languages.en_GB??? |
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頁(從 - 到) | 4122-4134 |
頁數 | 13 |
期刊 | Advanced Synthesis and Catalysis |
卷 | 364 |
發行號 | 23 |
DOIs | |
出版狀態 | 已出版 - 8 12月 2022 |
指紋
深入研究「Brønsted Acid-Promoted Benzannulation of o-Alkynylbenzaldehyde and Alkyne, and the Positive Effect of Propargyl Alcohol」主題。共同形成了獨特的指紋。資料集
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CCDC 2176243: Experimental Crystal Structure Determination
Chen, C.-C. (貢獻者), Kuan, T.-H. (貢獻者), Yuan, W.-W. (貢獻者), Chen, S.-E. (貢獻者), Fu, J.-C. (貢獻者), Chen, Y.-X. (貢獻者), Gavin Tsai, H.-H. (貢獻者) & Hou, D.-R. (貢獻者), Cambridge Crystallographic Data Centre, 2022
DOI: 10.5517/ccdc.csd.cc2c1kdd, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc2c1kdd&sid=DataCite
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CCDC 2123951: Experimental Crystal Structure Determination
Chen, C.-C. (貢獻者), Kuan, T.-H. (貢獻者), Yuan, W.-W. (貢獻者), Chen, S.-E. (貢獻者), Fu, J.-C. (貢獻者), Chen, Y.-X. (貢獻者), Gavin Tsai, H.-H. (貢獻者) & Hou, D.-R. (貢獻者), Cambridge Crystallographic Data Centre, 2022
DOI: 10.5517/ccdc.csd.cc2994kb, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc2994kb&sid=DataCite
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