TY - JOUR
T1 - Bimetallic PtM (M=Pd, Ir) nanoparticle decorated multi-walled carbon nanotube enzyme-free, mediator-less amperometric sensor for H 2O 2
AU - Chen, Kuan Jung
AU - Chandrasekara Pillai, K.
AU - Rick, John
AU - Pan, Chun Jern
AU - Wang, Shih Han
AU - Liu, Chung Chiun
AU - Hwang, Bing Joe
N1 - Funding Information:
The authors gratefully acknowledge the support from the National Science Council ( NSC-97-2120-M-011-001 and NSC-97-2221-E-011-075-MY3 ), the National Synchrotron Radiation Research Center (NSRRC) , the National Taiwan University of Science and Technology and Electronics Design Center of Case Western Reserve University.
PY - 2012/3/15
Y1 - 2012/3/15
N2 - A new highly catalytic and intensely sensitive amperometric sensor based on PtM (where M=Pd, Ir) bimetallic nanoparticles (NPs) for the rapid and accurate estimation of hydrogen peroxide (H 2O 2) by electrooxidation in physiological conditions is reported. PtPd and PtIr NPs-decorated multiwalled carbon nanotube nanocatalysts (PtM/MWCNTs) were prepared by a modified Watanabe method, and were characterized by XRD, TEM, ICP, and XAS. The sensors were constructed by immobilizing PtM/MWCNTs nanocatalysts in a Nafion film on a glassy carbon electrode. Both PtPd/MWCNTs and PtIr/MWCNTs assemblies catalyzed the electrochemical oxidation of H 2O 2. Cyclic voltammetry characterization measurements revealed that both the PtM (M=Pd, Ir)/MWCNTs/GCE possessed similar electrochemical surface areas (∼0.55cm 2), and electron transfer rate constants (∼1.23×10 -3cms -1); however, the PtPd sensor showed a better performance in H 2O 2 sensing than did the PtIr counterpart. Explanations were sought from XAS measurements to explain the reasons for differences in sensor activity. When applied to the electrochemical detection of H 2O 2, the PtPd/MWCNTs/GC electrode exhibited a low detection limit of 1.2μM with a wide linear range of 2.5-125μM (R 2=0.9996). A low working potential (0V (SCE)), fast amperometric response (<5s), and high sensitivity (414.8μAmM -1cm -2) were achieved at the PtPd/MWCNTs/GC electrode. In addition, the PtPd/MWCNTs nanocatalyst sensor electrode also exhibited excellent reproducibility and stability. Along with these attractive features, the sensor electrode also displayed very high specificity to H 2O 2 with complete elimination of interference from UA, AA, AAP and glucose.
AB - A new highly catalytic and intensely sensitive amperometric sensor based on PtM (where M=Pd, Ir) bimetallic nanoparticles (NPs) for the rapid and accurate estimation of hydrogen peroxide (H 2O 2) by electrooxidation in physiological conditions is reported. PtPd and PtIr NPs-decorated multiwalled carbon nanotube nanocatalysts (PtM/MWCNTs) were prepared by a modified Watanabe method, and were characterized by XRD, TEM, ICP, and XAS. The sensors were constructed by immobilizing PtM/MWCNTs nanocatalysts in a Nafion film on a glassy carbon electrode. Both PtPd/MWCNTs and PtIr/MWCNTs assemblies catalyzed the electrochemical oxidation of H 2O 2. Cyclic voltammetry characterization measurements revealed that both the PtM (M=Pd, Ir)/MWCNTs/GCE possessed similar electrochemical surface areas (∼0.55cm 2), and electron transfer rate constants (∼1.23×10 -3cms -1); however, the PtPd sensor showed a better performance in H 2O 2 sensing than did the PtIr counterpart. Explanations were sought from XAS measurements to explain the reasons for differences in sensor activity. When applied to the electrochemical detection of H 2O 2, the PtPd/MWCNTs/GC electrode exhibited a low detection limit of 1.2μM with a wide linear range of 2.5-125μM (R 2=0.9996). A low working potential (0V (SCE)), fast amperometric response (<5s), and high sensitivity (414.8μAmM -1cm -2) were achieved at the PtPd/MWCNTs/GC electrode. In addition, the PtPd/MWCNTs nanocatalyst sensor electrode also exhibited excellent reproducibility and stability. Along with these attractive features, the sensor electrode also displayed very high specificity to H 2O 2 with complete elimination of interference from UA, AA, AAP and glucose.
KW - Amperometric sensor
KW - H O estimation
KW - Pt-based bimetallic nanoparticles (NPs)
KW - PtPd NPs-decorated multi walled carbon nanotube electrode
UR - http://www.scopus.com/inward/record.url?scp=84857370614&partnerID=8YFLogxK
U2 - 10.1016/j.bios.2011.12.037
DO - 10.1016/j.bios.2011.12.037
M3 - 期刊論文
C2 - 22236778
AN - SCOPUS:84857370614
SN - 0956-5663
VL - 33
SP - 120
EP - 127
JO - Biosensors and Bioelectronics
JF - Biosensors and Bioelectronics
IS - 1
ER -