Bilayered membranes of Janus dendrimers with hybrid hydrogenated and fluorinated dendrons: Microstructures and coassembly with lipids

Yan Ling Yang, Yu Jane Sheng, Heng Kwong Tsao

研究成果: 雜誌貢獻期刊論文同行評審

7 引文 斯高帕斯(Scopus)

摘要

A biomimetic membrane formed by hybrid Janus dendrimers (JDs) which contain hydrogenated and fluorinated dendrons was explored by dissipative particle dynamics simulations. The JD membrane is bilayered and shows a bicontinuous morphology which is also observed in nano-sized dendrimersomes. The thickness of the dendrimersome is significantly less than that of the planar membrane. The co-assembly of lipids with JDs to develop a hybrid membrane was studied as well. Lipids tend to locate in the hydrocarbon domain of the bicontinuous structure of the JD-rich membrane, while 2-dimensional micelles of JDs float in the leaflet of the lipid-rich membrane. The microstructure of the hybrid membrane was quantified by interdigitation lengths in the hydrocarbon, fluorocarbon, and lipid domains. Finally, the influence of lipid concentration on lipid fluidity was examined in terms of lipid diffusivity, which is found to be closely associated with the membrane microstructure.

原文???core.languages.en_GB???
頁(從 - 到)15400-15407
頁數8
期刊Physical Chemistry Chemical Physics
21
發行號28
DOIs
出版狀態已出版 - 2019

指紋

深入研究「Bilayered membranes of Janus dendrimers with hybrid hydrogenated and fluorinated dendrons: Microstructures and coassembly with lipids」主題。共同形成了獨特的指紋。

引用此