A fully automated multidimensional protein separation system is presented as a high-throughput alternative to traditional 2-D PAGE for comprehensive protein profiling and biomarker discovery. Here we present recent developments enabling separation of complex protein mixtures using a new chip design, a substantially modified fabrication process including the use of UV-ozone surface treatments, and in situ photopolymerization of poly(ethylene glycol)-based gel plugs to control pressure induced flow in selected regions of the chip.
|出版狀態||已出版 - 2006|
|事件||10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan|
持續時間: 5 11月 2006 → 9 11月 2006
|???event.eventtypes.event.conference???||10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006|
|期間||5/11/06 → 9/11/06|