@article{66e2de1ce3cc46e19c930daed23cccc7,
title = "ATP-Dependent Dynamic Protein Aggregation Regulates Bacterial Dormancy Depth Critical for Antibiotic Tolerance",
abstract = "In this work, Pu et al. introduced a concept of “dormancy depth” that provides a unifying framework for understanding both persisters and viable but non-culturable cells. Subsequent mechanistic investigations revealed how ATP-dependent dynamic protein aggregation regulates cellular dormancy and resuscitation, the fine control of which facilitates bacterial drug tolerance.",
keywords = "ATP, DnaK-ClpB complex, bacterial antibiotic tolerance, cell resuscitation, dormancy depth, persisters, protein aggregates, viable but non-culturable cells",
author = "Yingying Pu and Yingxing Li and Xin Jin and Tian Tian and Qi Ma and Ziyi Zhao and Lin, {Ssu yuan} and Zhanghua Chen and Binghui Li and Guang Yao and Leake, {Mark C.} and Lo, {Chien Jung} and Fan Bai",
note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",
year = "2019",
month = jan,
day = "3",
doi = "10.1016/j.molcel.2018.10.022",
language = "???core.languages.en_GB???",
volume = "73",
pages = "143--156.e4",
journal = "Molecular Cell",
issn = "1097-2765",
number = "1",
}