Addition of dissimilar carbenes across an unsymmetrically substituted alkyne: Regio-and stereoselective synthesis of trisubstituted 1,3-dienes

Joseph M. O'Connor, Ming Chou Chen, Ryan L. Holland, Arnold L. Rheingold

研究成果: 雜誌貢獻期刊論文同行評審

8 引文 斯高帕斯(Scopus)

摘要

The formal addition of dissimilar carbenes across an unsymmetrically substituted alkyne has been achieved for the first time by a two-step sequence in which a cobalt-alkyne complex undergoes reaction with a carbene addend (CHR1) to give a metallacyclobutene complex, followed by reaction with a second carbene addend (CHR2) to give a mixture of diene complexes. In situ treatment of the diene mixture with fluoride leads to desilylation and conversion to a single cobalt-diene complex with a high degree of regio-and stereoselectivity.

原文???core.languages.en_GB???
頁(從 - 到)369-371
頁數3
期刊Organometallics
30
發行號3
DOIs
出版狀態已出版 - 14 2月 2011

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