Activation of the checkpoint kinase Rad53 by the phosphatidyl inositol kinase-like kinase Mec1

Keyphrases

• Amores 8%
• Autophosphorylation 16%
• Checkpoint Kinase 1 (CHK1) 100%
• Checkpoint Pathway 8%
• Chk2 25%
• Concentration-dependent 8%
• DNA Damage 25%
• DNA Damage Checkpoint 8%
• Essential Proteins 8%
• Fold Increase 8%
• Immune Complex 8%
• Kinase Activity 8%
• Kinase-independent 16%
• Kinetic Analysis 8%
• Mec1 100%
• Oligomerization 8%
• Orthologs 25%
• Phosphatidylinositol Kinase 100%
• Phosphorylation 33%
• Pre-incubation 8%
• Protein Kinase 8%
• Protein Kinase Activity 8%
• Rad53 100%
• Saccharomyces Cerevisiae 8%

Biochemistry, Genetics and Molecular Biology

• Antigen Antibody Complex 12%
• Autophosphorylation 25%
• DNA Damage 25%
• DNA Damage Response 12%
• DNA Synthesis 12%
• Kinase 100%
• Oligomerization 12%
• Orthology 37%
• Phosphatidylinositol 100%
• Phosphotransferase 100%
• Protein Kinases 25%
• Saccharomyces cerevisiae 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Phosphatidylinositol Kinase 100%
• Phosphotransferase 100%
• Protein Kinases 33%
• Saccharomyces cerevisiae 16%