Activation of multiple apoptotic pathways in human nasopharyngeal carcinoma cells by the prenylated isoflavone, osajin

Biochemistry, Genetics and Molecular Biology

• Cell Death 100%
• Isoflavone 100%
• Programmed Cell Death 100%
• Mitochondrion 50%
• Upregulation 50%
• Antineoplastic Activity 50%
• Cancer Cell 50%
• Downregulation 50%
• Glucose-Regulated Protein 50%
• Bcl-2 50%
• Membrane Potential 50%
• Fas Ligand 50%
• Endoplasmic Reticulum Stress 50%
• Bcl-2-Associated X Protein 50%
• Caspase-9 50%
• Cytochrome C 50%

Keyphrases

• Nasopharyngeal Carcinoma Cells 100%
• Apoptotic Pathway 100%
• Prenylated Isoflavones 100%
• Osajin 100%
• Induced Apoptosis 25%
• Mitochondria 12%
• Human Nasopharyngeal Carcinoma 12%
• Caspase-9 12%
• Antitumor Activity 12%
• Chemopreventive 12%
• Tumor Cell Lines 12%
• Endoplasmic Reticulum Stress (ER stress) 12%
• Induced Cell Death 12%
• Effective Compounds 12%
• Significant Loss 12%
• Glucose-regulated Protein 78 (GRP78) 12%
• Fas Ligand 12%
• Cytochrome c (Cyt c) 12%
• Intrinsic Pathway 12%
• Death Receptor Pathway 12%
• Mitochondrial Transmembrane Potential 12%
• Cancer Cell Death 12%
• Pro-apoptotic 12%
• Molecular Effects 12%
• Enhanced Expression 12%
• Anti-apoptotic Bcl-2 12%
• Bax Protein 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Nasopharynx Carcinoma 100%
• Isoflavone 100%
• Neoplasm 20%
• Malignant Neoplasm 20%
• Caspase 9 20%
• Antitumor Activity 20%
• Cytochrome C 20%
• Glucose Regulated Protein 78 20%
• Fas Ligand 20%
• Death Receptor 20%
• Protein Bcl 2 20%
• Protein Bax 20%
• Antiapoptotic 20%