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先導化合物與目標分子作用之熱力學與結構以引導合理抗癌藥物設計之研究(1/3)
Chen, Wen-Yih
(PI)
化學工程與材料工程學系
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Keyphrases
Target Interaction
100%
Anticancer Drugs
100%
Lithuanian
100%
Pharmaceutical Compounds
100%
Lead Target
100%
Drug Design
100%
Latvian
66%
Protein Targeting
66%
Taiwanese
66%
Illness
66%
Gibbs Free Energy
66%
Human Target
33%
Disease Targets
33%
Histone Deacetylases
33%
Recombinant Protein
33%
SAR Analysis
33%
Fundamental Science
33%
Protein Clusters
33%
Natural Compounds
33%
Drug Interactions
33%
Isothermal Titration Calorimetry
33%
Pharmaceutical Industry
33%
Protein-ligand
33%
Hit Compound
33%
Group by
33%
Number of Drugs
33%
Organic Synthesis
33%
Thermodynamic Data
33%
Drug Costs
33%
Novel Protocol
33%
Thermodynamic Correlation
33%
Thermodynamics
33%
Synthetic Compounds
33%
Enzymatic Activity
33%
Bacterial Cells
33%
Matrix Metalloproteinases
33%
Carbonic Anhydrase
33%
IC50
33%
Pharmaceutical Companies
33%
High Affinity
33%
Binding Properties
33%
Cancer-related Inflammation
33%
Glaucoma
33%
Human Cells
33%
Molecular Interactions
33%
High-throughput Screening
33%
Fluorescent Thermal Shift Assay
33%
Further Development
33%
Biochemistry, Genetics and Molecular Biology
Anticancer
100%
Energy Transfer
100%
Protein Ligand
50%
Structure Activity Relation
50%
High Throughput Screening
50%
Isothermal Titration Calorimetry
50%
Histone Deacetylase
50%
Enthalpy
50%
IC50
50%
Matrix Metalloproteinase
50%
Recombinant Protein
50%
Drug Interaction
50%
Molecular Interaction
50%
Enzyme Activity
50%
Carbonic Anhydrase
50%
Pharmacology, Toxicology and Pharmaceutical Science
Disease
100%
Drug Development
75%
Lead Compound
50%
IC50
25%
Drug Interaction
25%
Recombinant Protein
25%
Malignant Neoplasm
25%
Calorimetry
25%
Side Effect
25%
Inflammation
25%
Drug
25%
Glaucoma
25%
Histone Deacetylase
25%
Matrix Metalloproteinase
25%
Protein Ligand
25%
Carbonate Dehydratase
25%
High-Throughput Screening
25%
Structure Activity Relationship
25%