Brevipolides之合成與製備具有生物活性之新型天然物

Keyphrases

1. Olefin Isomerization 66%
2. Palladium(0) 66%
3. Eicosanoids 66%
4. Allylic Oxidation 66%
5. Dimethylsulfoxonium Methylide 66%
6. Thioesterification 66%
7. Microwave-assisted 66%
8. Phthalides 66%
9. Thioester 66%
10. Enantioselective Synthesis 66%
11. Cyclopropanation 66%
12. Nanoparticles 66%
13. Anti-addition 66%
14. Acid-base 66%
15. Formal Synthesis 66%
16. Carboxylic Acids 66%
17. Unsaturated Ketones 66%
18. Isomerization Reaction 50%
19. Alkyl Halides 44%
20. Sharpless Epoxidation 33%
21. NMR Kinetics 33%
22. Sp3 Carbon 33%
23. Epoxide Ring Opening 33%
24. (E)-Alkene 33%
25. Cross-metathesis 33%
26. Corey-Chaykovsky Reaction 33%
27. Tert-Butyldimethylsilyl 33%
28. Dihydroisocoumarins 33%
29. Enantiomerically Pure 33%
30. Carboxylic Acid Esters 33%
31. Epoxides 33%
32. Acid Derivatives 33%
33. Tertiary Amides 33%
34. X-ray Powder Diffraction 33%
35. Esterification 33%
36. Allyl 33%
37. Pd Nanoparticles 33%
38. Sulfur Ylides 33%
39. Enones 33%
40. Benzene Ring 33%
41. Olefins 33%
42. Spectroscopic Data 33%
43. Tert 33%
44. Benzoic Acid 33%
45. In Situ 33%
46. Target Molecule 33%
47. Carbon Atom 33%
48. Stereochemical Assignment 33%
49. Kinetic Model 33%
50. Ring-closing Metathesis 33%
51. X-ray Crystallography 33%
52. Diastereoselectivity 33%
53. Protecting Groups 33%
54. 1H NMR Studies 33%
55. Penta 33%
56. Propylene 33%
57. Stepwise Procedure 33%
58. Scanning Electron Microscopy Analysis 33%
59. PdCl2 33%
60. Quaternary Ammonium Salt 22%
61. 4-Dimethylaminopyridine 22%
62. Diphenylthiourea 22%
63. Aromatic Carboxylic Acid 22%
64. Aliphatic Carboxylic Acids 22%
65. New Reaction Mechanism 22%
66. Reaction Intermediates 22%
67. Functional Groups 22%
68. Triethylamine 22%
69. Tertiary Amine 22%
70. Microwave Heating 22%
71. One-pot Synthesis 22%
72. Kinetic Isotope Effect 16%
73. Wacker 16%
74. Selective Formation 16%
75. Isocoumarin 16%
76. Wacker Oxidation 16%
77. C-H Cleavage 16%
78. Palladium 16%
79. Mechanistic Studies 16%
80. Reaction Conditions 16%
81. Acetate 16%
82. Ethane 16%
83. Natural Products 16%
84. Ethyl 16%

Chemistry

1. Isomerization 100%
2. Alkene 100%
3. Palladium 100%
4. Carboxylic Acid 88%
5. Eicosanoid 66%
6. Thioester 66%
7. Epoxide 66%
8. Nanoparticle 66%
9. Base 66%
10. Benzoic Acid 66%
11. Ketones 66%
12. Halide 44%
13. Corey-Chaykovsky Ring Formation 33%
14. Isocoumarin 33%
15. Kinetic Isotope Effect 33%
16. Sharpless Epoxidation 33%
17. Cross Metathesis 33%
18. Ring Opening Reaction 33%
19. Cyclopropane 33%
20. Substance Spectroscopy 33%
21. Diastereoselectivity 33%
22. Protecting Groups 33%
23. Ring Closing Metathesis 33%
24. Enone 33%
25. Sulfur Ylide 33%
26. Mechanistic Study 33%
27. Occurrence in Nature 33%
28. Purity 33%
29. Ethyl 33%
30. Esterification 33%
31. X-Ray Crystallography 33%
32. Triethylamine 22%
33. Tertiary Amide 22%
34. Dihydroisocoumarins 22%
35. Benzene Ring 22%
36. Electron Microscopy 22%
37. Tertiary Amine 22%
38. Reaction Intermediate 22%
39. Quaternary Ammonium Salt 22%
40. Scanning Electron Microscopy 22%
41. 1H NMR Spectroscopy 22%
42. Carbon Atom 22%
43. One Pot Reaction 22%
44. Powder X-Ray Diffraction 22%