Wen-Yih Chen

2023

Molecular effects of site-specific phosphate-methylated primer on the structure and motions of Taq DNA polymerase

Tsai, Y. C., Chen, W. Y. & Chiu, C. C., 1月 2023, 於: Computational and Structural Biotechnology Journal. 21, p. 1820-1827 8 p.

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Ultrasensitive Detection of Interleukin 6 by Using Silicon Nanowire Field-Effect Transistors

Hu, W. P., Wu, Y. M., Vu, C. A. & Chen, W. Y., 1月 2023, 於: Sensors (Switzerland). 23, 2, 625.

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2 引文斯高帕斯（Scopus）

2022

Increasing the λ-Red mediated gene deletion efficiency in Escherichia coli using methyl phosphotriester-modified DNA

Chou, S. C., Lai, Y. J., Zhuo, X. Z., Chen, W. Y. & Li, S. Y., 8月 2022, 於: Journal of the Taiwan Institute of Chemical Engineers. 137, 104297.

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3 引文斯高帕斯（Scopus）

In-Silico Selection of Aptamer Targeting SARS-CoV-2 Spike Protein

Lin, Y. C., Chen, W. Y., Hwu, E. T. & Hu, W. P., 1 5月 2022, 於: International Journal of Molecular Sciences. 23, 10, 5810.

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3 引文斯高帕斯（Scopus）

Optimizing surface modification of silicon nanowire field-effect transistors by polyethylene glycol for MicroRNA detection

Vu, C. A., Lai, H. Y., Chang, C. Y., Chan, H. W. H. & Chen, W. Y., 1月 2022, 於: Colloids and Surfaces B: Biointerfaces. 209, 112142.

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6 引文斯高帕斯（Scopus）

Paper-Based Devices for Capturing Exosomes and Exosomal Nucleic Acids From Biological Samples

Lai, C. H., Lee, C. L., Vu, C. A., Vu, V. T., Tsai, Y. H., Chen, W. Y. & Cheng, C. M., 12 4月 2022, 於: Frontiers in Bioengineering and Biotechnology. 10, 836082.

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2 引文斯高帕斯（Scopus）

Real-time changes in the AC magnetic susceptibility of reagents during immunomagnetic reduction assays

Chen, H. H., Hsu, M. H., Lee, K. H., Chen, W. Y. & Yang, S. Y., 1 6月 2022, 於: AIP Advances. 12, 6, 065220.

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2 引文斯高帕斯（Scopus）

2021

Improved biomarker quantification of silicon nanowire field-effect transistor immunosensors with signal enhancement by RNA aptamer: Amyloid beta as a case study

Vu, C. A., Chen, W. Y., Yang, Y. S. & Chan, H. W. H., 15 2月 2021, 於: Sensors and Actuators, B: Chemical. 329, 129150.

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13 引文斯高帕斯（Scopus）

Switching the Inhibitor-Enzyme Recognition Profile via Chimeric Carbonic Anhydrase XII

Smirnovienė, J., Smirnov, A., Zakšauskas, A., Zubrienė, A., Petrauskas, V., Mickevičiūtė, A., Michailovienė, V., Čapkauskaitė, E., Manakova, E., Gražulis, S., Baranauskienė, L., Chen, W. Y., Ladbury, J. E. & Matulis, D., 5月 2021, 於: ChemistryOpen. 10, 5, p. 567-580 14 p.

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1 引文斯高帕斯（Scopus）

Uncertainty in protein–ligand binding constants: asymmetric confidence intervals versus standard errors

Paketurytė, V., Petrauskas, V., Zubrienė, A., Abian, O., Bastos, M., Chen, W. Y., Moreno, M. J., Krainer, G., Linkuvienė, V., Sedivy, A., Velazquez-Campoy, A., Williams, M. A. & Matulis, D., 5月 2021, 於: European Biophysics Journal. 50, 3-4, p. 661-670 10 p.

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16 引文斯高帕斯（Scopus）

2020

Improve sample preparation process for miRNA isolation from the culture cells by using silica fiber membrane

Hu, W. P., Chen, Y. C. & Chen, W. Y., 12月 2020, 於: Scientific Reports. 10, 1, 21132.

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10 引文斯高帕斯（Scopus）

Reduction of interstrand charge repulsion of DNA duplexes by salts and by neutral phosphotriesters – Contrary effects for harnessing duplex formation

Kuo, T. C., Wu, M. W., Lin, W. C., Matulis, D., Yang, Y. S., Li, S. Y. & Chen, W. Y., 5月 2020, 於: Journal of the Taiwan Institute of Chemical Engineers. 110, p. 1-7 7 p.

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7 引文斯高帕斯（Scopus）

Studies of the interactions mechanism between DNA and silica surfaces by Isothermal Titration Calorimetry

Chen, W. Y., Matulis, D., Hu, W. P., Lai, Y. F. & Wang, W. H., 11月 2020, 於: Journal of the Taiwan Institute of Chemical Engineers. 116, p. 62-66 5 p.

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6 引文斯高帕斯（Scopus）

2019

Designed phosphate-methylated oligonucleotides as PCR primers for SNP discrimination

Li, T. L., Wu, M. W., Lin, W. C., Lai, C. H., Chang, Y. H., Su, L. J. & Chen, W. Y., 19 7月 2019, 於: Analytical and Bioanalytical Chemistry. 411, 17, p. 3871-3880 10 p.

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11 引文斯高帕斯（Scopus）

Molecular self-interactions of ribonuclease A revealed by isothermal titration calorimetry and self-interaction chromatography – Effects of anisotropy of protein surface charges

Kuo, T. C., Huang, Y. C., Matulis, D. & Chen, W. Y., 3月 2019, 於: Journal of the Taiwan Institute of Chemical Engineers. 96, p. 74-81 8 p.

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1 引文斯高帕斯（Scopus）

Neutralized chimeric DNA probe for the improvement of GC-rich RNA detection specificity on the nanowire field-effect transistor

Chou, W. C., Hu, W. P., Yang, Y. S., Chan, H. W. H. & Chen, W. Y., 1 12月 2019, 於: Scientific Reports. 9, 1, 11056.

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13 引文斯高帕斯（Scopus）

Repeatability, precision, and accuracy of the enthalpies and Gibbs energies of a protein–ligand binding reaction measured by isothermal titration calorimetry

Paketurytė, V., Linkuvienė, V., Krainer, G., Chen, W. Y. & Matulis, D., 4 3月 2019, 於: European Biophysics Journal. 48, 2, p. 139-152 14 p.

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10 引文斯高帕斯（Scopus）

Signal Enhancement of Silicon Nanowire Field-Effect Transistor Immunosensors by RNA Aptamer

Vu, C. A., Hu, W. P., Yang, Y. S., Chan, H. W. H. & Chen, W. Y., 17 9月 2019, 於: ACS Omega. 4, 12, p. 14765-14771 7 p.

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18 引文斯高帕斯（Scopus）

2018

Neutralized chimeric DNA probe for detection of single nucleotide polymorphism on surface plasmon resonance biosensor

Huang, C. J., Lin, Z. E., Yang, Y. S., Chan, H. W. H. & Chen, W. Y., 15 1月 2018, 於: Biosensors and Bioelectronics. 99, p. 170-175 6 p.

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28 引文斯高帕斯（Scopus）

Synergetic improvements of sensitivity and specificity of nanowire field effect transistor gene chip by designing neutralized DNA as probe

Hu, W. P., Tsai, C. C., Yang, Y. S., Chan, H. W. H. & Chen, W. Y., 1 12月 2018, 於: Scientific Reports. 8, 1, 12598.

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11 引文斯高帕斯（Scopus）

2017

Nanostructured silicon substrate for desorption/ionization on silicon mass spectrometry coupled with titanium oxide and zinc oxide coated magnetic nanoparticles for phosphopeptide analysis

Tsao, C. W., Chen, W. Y., Lin, C. H. & Cheng, Y. C., 1 3月 2017, 於: Journal of Nanoscience and Nanotechnology. 17, 3, p. 2054-2060 7 p.

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1 引文斯高帕斯（Scopus）

The Combination of Computational and Biosensing Technologies for Selecting Aptamer against Prostate Specific Antigen

Hsieh, P. C., Lin, H. T., Chen, W. Y., Tsai, J. J. P. & Hu, W. P., 2017, 於: BioMed Research International. 2017, 5041683.

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11 引文斯高帕斯（Scopus）

Tunable PEGylation of branch-type PEI/DNA polyplexes with a compromise of low cytotoxicity and high transgene expression: In vitro and in vivo gene delivery

Venault, A., Huang, Y. C., Lo, J. W., Chou, C. J., Chinnathambi, A., Higuchi, A., Chen, W. S., Chen, W. Y. & Chang, Y., 2017, 於: Journal of Materials Chemistry B. 5, 24, p. 4732-4744 13 p.

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19 引文斯高帕斯（Scopus）

2016

A replaceable liposomal aptamer for the ultrasensitive and rapid detection of biotin

Sung, T. C., Chen, W. Y., Shah, P. & Chen, C. S., 23 2月 2016, 於: Scientific Reports. 6, 21369.

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13 引文斯高帕斯（Scopus）

Isothermal titration calorimetry for drug design: Precision of the enthalpy and binding constant measurements and comparison of the instruments

Linkuvienė, V., Krainer, G., Chen, W. Y. & Matulis, D., 15 12月 2016, 於: Analytical Biochemistry. 515, p. 61-64 4 p.

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34 引文斯高帕斯（Scopus）

2015

Computational selection of RNA aptamer against angiopoietin-2 and experimental evaluation

Hu, W. P., Kumar, J. V., Huang, C. J. & Chen, W. Y., 2015, 於: BioMed Research International. 2015, 658712.

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35 引文斯高帕斯（Scopus）

The consideration of indolicidin modification to balance its hemocompatibility and delivery efficiency

Tsai, C. W., Hu, W. W., Liu, C. I., Ruaan, R. C., Tsai, B. C., Jin, S. L. C., Chang, Y. & Chen, W. Y., 15 10月 2015, 於: International Journal of Pharmaceutics. 494, 1, p. 498-505 8 p.

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7 引文斯高帕斯（Scopus）

2014

A polarization control system for intensity-resolved guided mode resonance sensors

Lin, S. F., Chang, F. C., Chen, Z. H., Wang, C. M., Yang, T. H., Chen, W. Y. & Chang, J. Y., 12 3月 2014, 於: Sensors (Switzerland). 14, 3, p. 5198-5206 9 p.

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11 引文斯高帕斯（Scopus）

Hydrostatic pressure enhances mitomycin C induced apoptosis in urothelial carcinoma cells

Chen, S. K., Chung, C. A., Cheng, Y. C., Huang, C. J., Ruaan, R. C., Chen, W. Y., Li, C., Tsao, C. W., Hu, W. W. & Chien, C. C., 1月 2014, 於: Urologic Oncology: Seminars and Original Investigations. 32, 1, p. 26.e17-26.e24

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9 引文斯高帕斯（Scopus）

Modification of silicone elastomer with zwitterionic silane for durable antifouling properties

Yeh, S. B., Chen, C. S., Chen, W. Y. & Huang, C. J., 30 9月 2014, 於: Langmuir. 30, 38, p. 11386-11393 8 p.

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122 引文斯高帕斯（Scopus）

PEGylation site-dependent structural heterogeneity study of MonoPEGylated human parathyroid hormone fragment hPTH(1-34)

Liu, C. Y., Li, X., Chen, W. Y., Chang, L. C., Chen, Y. F., Chen, H. L., Sun, Y. S., Lai, H. Y. & Huang, E. W., 30 9月 2014, 於: Langmuir. 30, 38, p. 11421-11427 7 p.

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2 引文斯高帕斯（Scopus）

Strategy of Fc-recognizable peptide ligand design for oriented immobilization of antibody

Tsai, C. W., Jheng, S. L., Chen, W. Y. & Ruaan, R. C., 18 3月 2014, 於: Analytical Chemistry. 86, 6, p. 2931-2938 8 p.

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24 引文斯高帕斯（Scopus）

The regulation of DNA adsorption and release through chitosan multilayers

Hu, W. W., Chen, Y. J., Ruaan, R. C., Chen, W. Y., Cheng, Y. C. & Chien, C. C., 2014, 於: Carbohydrate Polymers. 99, p. 394-402 9 p.

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13 引文斯高帕斯（Scopus）

Toll-like receptor 6 and connective tissue growth factor are significantly upregulated in mitomycin-C-treated urothelial carcinoma cells under hydrostatic pressure stimulation

Chen, S. K., Chung, C. A., Cheng, Y. C., Huang, C. J., Chen, W. Y., Ruaan, R. C., Li, C., Tsao, C. W., Hu, W. W. & Chien, C. C., 1 6月 2014, 於: Genetic Testing and Molecular Biomarkers. 18, 6, p. 410-416 7 p.

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10 引文斯高帕斯（Scopus）

2013

A model for fast predicting and optimizing the sensitivity of surface-relief guided mode resonance sensors

Lin, S. F., Wang, C. M., Tsai, Y. L., Ding, T. J., Yang, T. H., Chen, W. Y., Yeh, S. F. & Chang, J. Y., 2013, 於: Sensors and Actuators, B: Chemical. 176, p. 1197-1203 7 p.

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30 引文斯高帕斯（Scopus）

A novel application of indolicidin for gene delivery

Hu, W. W., Lin, Z. W., Ruaan, R. C., Chen, W. Y., Jin, S. L. C. & Chang, Y., 2013, 於: International Journal of Pharmaceutics. 456, 2, p. 293-300 8 p.

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13 引文斯高帕斯（Scopus）

Improved DNA detection by utilizing electrically neutral DNA probe in field-effect transistor measurements as evidenced by surface plasmon resonance imaging

Chen, W. Y., Chen, H. C., Yang, Y. S., Huang, C. J., Chan, H. W. H. & Hu, W. P., 15 3月 2013, 於: Biosensors and Bioelectronics. 41, 1, p. 795-801 7 p.

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22 引文斯高帕斯（Scopus）

Kosmotrope-like hydration behavior of polyethylene glycol from microcalorimetry and binding isotherm measurements

Chen, W. Y., Hsu, M. Y., Tsai, C. W., Chang, Y., Ruaan, R. C., Kao, W. H., Huang, E. W. & Chung Chuan, H. Y. T., 2 4月 2013, 於: Langmuir. 29, 13, p. 4259-4265 7 p.

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17 引文斯高帕斯（Scopus）

Salt bridge exchange binding mechanism between streptavidin and its DNA aptamer - Thermodynamics and spectroscopic evidences

Kuo, T. C., Lee, P. C., Tsai, C. W. & Chen, W. Y., 3月 2013, 於: Journal of Molecular Recognition. 26, 3, p. 149-159 11 p.

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9 引文斯高帕斯（Scopus）

2012

Bioadhesive control of plasma proteins and blood cells from umbilical cord blood onto the interface grafted with zwitterionic polymer brushes

Chang, Y., Chang, Y., Higuchi, A., Shih, Y. J., Li, P. T., Chen, W. Y., Tsai, E. M. & Hsiue, G. H., 6 3月 2012, 於: Langmuir. 28, 9, p. 4309-4317 9 p.

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47 引文斯高帕斯（Scopus）

Biofouling resistance of ultrafiltration membranes controlled by surface self-assembled coating with PEGylated copolymers

Chiag, Y. C., Chang, Y., Chen, W. Y. & Ruaan, R. C., 17 1月 2012, 於: Langmuir. 28, 2, p. 1399-1407 9 p.

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84 引文斯高帕斯（Scopus）

Molecular dynamics simulation of the induced-fit binding process of DNA aptamer and L-argininamide

Lin, P. H., Tsai, C. W., Wu, J. W., Ruaan, R. C. & Chen, W. Y., 11月 2012, 於: Biotechnology Journal. 7, 11, p. 1367-1375 9 p.

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24 引文斯高帕斯（Scopus）

Monitoring DNA hybridization with a simply manufactured GMR biosensor

Ding, T. J., Lue, J. H., Tsai, Y. L., Yang, T. H., Chang, J. Y. & Chen, W. Y., 25 6月 2012, 於: Life Science Journal. 9, 2, p. 1015-1019 5 p.

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4 引文斯高帕斯（Scopus）

Nanostructured silicon surface modifications for as a selective matrix-free laser desorption/ionization mass spectrometry

Tsao, C. W., Lin, C. H., Cheng, Y. C., Chien, C. C., Chang, C. C. & Chen, W. Y., 7 6月 2012, 於: Analyst. 137, 11, p. 2643-2650 8 p.

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11 引文斯高帕斯（Scopus）

Optimization of DNA-directed immobilization on mixed oligo(ethylene glycol) monolayers for immunodetection

Hu, W. P., Huang, L. Y., Kuo, T. C., Hu, W. W., Chang, Y., Chen, C. S., Chen, H. C. & Chen, W. Y., 1 4月 2012, 於: Analytical Biochemistry. 423, 1, p. 26-35 10 p.

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14 引文斯高帕斯（Scopus）

Rapid analysis of abused drugs using nanostructured silicon surface assisted laser desorption/ionization mass spectrometry

Cheng, Y. C., Chen, K. H., Wang, J. S., Hsu, W. L., Chien, C. C., Chen, W. Y. & Tsao, C. W., 7 2月 2012, 於: Analyst. 137, 3, p. 654-661 8 p.

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30 引文斯高帕斯（Scopus）

Retention prediction of peptide diastereomers in reversed-phase liquid chromatography assisted by molecular dynamics simulation

Tsai, C. W., Chen, W. Y. & Ruaan, R. C., 25 9月 2012, 於: Langmuir. 28, 38, p. 13601-13608 8 p.

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3 引文斯高帕斯（Scopus）

Sensitive metal layer assisted guided mode resonance biosensor with a spectrum inversed response and strong asymmetric resonance field distribution

Lin, S. F., Wang, C. M., Ding, T. J., Tsai, Y. L., Yang, T. H., Chen, W. Y. & Chang, J. Y., 18 6月 2012, 於: Optics Express. 20, 13, p. 14584-14593 10 p.

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45 引文斯高帕斯（Scopus）

Structural stability-chromatographic retention relationship on exenatide diastereomer separation

Tsai, C. W., Kao, W. H., Chang, L. C., Ruaan, R. C. & Chen, W. Y., 11月 2012, 於: Analytical and Bioanalytical Chemistry. 404, 8, p. 2437-2444 8 p.

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2 引文斯高帕斯（Scopus）

Use of a kinesin-cro fusion protein as the nanoshuttle to transport specific DNA

Tsai, M. C., Wu, J. Y., Lin, H. C., Chen, T. H., Hsieh, Y. H., Shih, C. M., Chen, W. Y., Huang, R. N. & Kuo, T. C., 2012, 於: Current Nanoscience. 8, 5, p. 669-675 7 p.

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