Benzamines are the major aromatic amines used in industry and can also be released from azo dyes, which are widely used in the textile, paper- making, and food industries. The toxicity of 10 benzamines was tested by the well diffusion assay technique against 18 common bacterial species including the nitrogen-fixing bacterium Azotobacter vinelandii. p-Phenylenediamine was found to be inhibitory to the growth of Aeromonas hydrophila and Pseudomonas fluorescens. o-Phenylenediamine was inhibitory to Escherichia coli, Klebsiella pnemoniae, Salmonella enteritidis, and Shigella sonnei. 2,5- Diaminotoluene was inhibitory to the growth of P. fluorescens and Streptococcus mitis. The growth of A. vinelandii was inhibited by p- phenylenediamine and 2,5-diaminotoluene in the well diffusion assay. p- Nitroaniline was also found to be inhibitory to the growth of A. vinelandii in Burk's nitrogen-free medium. The nitrogenase activity of A. vinelandii was inhibited by p-phenylenediamine, 2,5-diaminotoluene, p-nitroaniline, 2- nitro-p-phenylenediamine, 3-nitro-o-phenylenediamine, and 4-nitro-o- phenylenediamine. Because many of these organisms are common soil and aquatic bacteria, the accumulation of these benzamine compounds in the environment may have an adverse impact on soil biochemical activities.
|Number of pages||4|
|Journal||Environmental Toxicology and Chemistry|
|State||Published - Jul 1997|
- Azotobacter vinelandii