TY - JOUR

T1 - Theoretical determination of the strength of soft noncovalent molecular bonds

AU - Chen, Hsuan Yi

AU - Chu, Yi Ping

PY - 2005/1

Y1 - 2005/1

N2 - The strength of a simple soft bond under a constant loading rate is studied theoretically. There is a scaling regime where rebinding is negligible and the rupture force scales as const+[ln(ku)] 2/3, where kv is the loading rate. The scaling regime is smaller for weaker bonds and broader for stronger bonds. For a loading rate beyond the upper limit of the scaling regime, the bond rupture is deterministic and the thermal effects are negligible. For a loading rate below the lower limit of the scaling regime, the contribution from rebinding becomes important and there is no simple scaling relation between the rupture force and the loading rate. Our theory takes the effect of rebinding in the calculation, therefore we find good agreement between theory and simulation even below the scaling regime.

AB - The strength of a simple soft bond under a constant loading rate is studied theoretically. There is a scaling regime where rebinding is negligible and the rupture force scales as const+[ln(ku)] 2/3, where kv is the loading rate. The scaling regime is smaller for weaker bonds and broader for stronger bonds. For a loading rate beyond the upper limit of the scaling regime, the bond rupture is deterministic and the thermal effects are negligible. For a loading rate below the lower limit of the scaling regime, the contribution from rebinding becomes important and there is no simple scaling relation between the rupture force and the loading rate. Our theory takes the effect of rebinding in the calculation, therefore we find good agreement between theory and simulation even below the scaling regime.

UR - http://www.scopus.com/inward/record.url?scp=41349122825&partnerID=8YFLogxK

U2 - 10.1103/PhysRevE.71.010901

DO - 10.1103/PhysRevE.71.010901

M3 - 期刊論文

C2 - 15697572

AN - SCOPUS:41349122825

VL - 71

JO - Physical Review E - Statistical, Nonlinear, and Soft Matter Physics

JF - Physical Review E - Statistical, Nonlinear, and Soft Matter Physics

SN - 1539-3755

IS - 1

M1 - 010901

ER -