The reusable glucose fiber sensor for the glucose absolute concentration measurement with heterodyne interferometry

Cheng Chih Hsu, Shou Heng Liang, Ju Yi Lee, Chyan Chyi Wu, Mao Chen Liu

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

In this paper, we developed a fiber type system for glucose absolute concentration measurement that integrated a pair of fiber sensors and heterodyne interferometry. The pair of the fiber sensors was constructed of single mode fibers which immobilized the glucose oxidase (GOx) on the core. Our studies show that the response time and resolution will be highly affected by the pH properties between the testing sample and GOx of the fiber sensor. The best response time of the fiber sensor are 1.3 seconds for glucose solution as the pH values of testing solution and GOx of the fiber sensor are identical. In addition, the results show good linearity of the calibration curve for the glucose solution and serum based sample. The best resolutions are 0.141 and 0.152 mg/dl for glucose solution and serum based sample, respectively. Besides, the fiber sensor can be reused more than 10 times in this study.

Original languageEnglish
Title of host publicationSICE 2011 - SICE Annual Conference 2011, Final Program and Abstracts
PublisherSociety of Instrument and Control Engineers (SICE)
Pages2307-2312
Number of pages6
ISBN (Print)9784907764395
StatePublished - 2011
Event50th Annual Conference on Society of Instrument and Control Engineers, SICE 2011 - Tokyo, Japan
Duration: 13 Sep 201118 Sep 2011

Publication series

NameProceedings of the SICE Annual Conference

Conference

Conference50th Annual Conference on Society of Instrument and Control Engineers, SICE 2011
Country/TerritoryJapan
CityTokyo
Period13/09/1118/09/11

Keywords

  • biosensor
  • interferometer
  • optical fiber sensor
  • phase detection

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