The periodical shear environment of a cone-and-plate bioreactor

C. A. Chung; C. S. Weng; M. Z. Tu

doi:10.1115/1.2170127

The periodical shear environment of a cone-and-plate bioreactor

C. A. Chung, C. S. Weng, M. Z. Tu

Department of Mechanical Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

We investigate theoretically the periodic shear environment of a cone-and-plate bioreactor. The imposed frequency is designated to reflect the periodic nature of mammalian cardiac cycles. The working formula obtained for the distribution of shear stresses shall be of substantial interest for applying periodic shear stresses to cell cultures in vitro.

Original language	English
Pages (from-to)	388-393
Number of pages	6
Journal	Journal of Fluids Engineering, Transactions of the ASME
Volume	128
Issue number	2
DOIs	https://doi.org/10.1115/1.2170127
State	Published - Mar 2006

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abstract = "We investigate theoretically the periodic shear environment of a cone-and-plate bioreactor. The imposed frequency is designated to reflect the periodic nature of mammalian cardiac cycles. The working formula obtained for the distribution of shear stresses shall be of substantial interest for applying periodic shear stresses to cell cultures in vitro.",

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The periodical shear environment of a cone-and-plate bioreactor

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