TY - JOUR
T1 - The age distribution from continuous biochemical reactors with cell reproduction by mitosis
AU - Chiang, Anthony S.T.
AU - Thompson, Robert W.
PY - 1981/3/21
Y1 - 1981/3/21
N2 - In this study we examine the operation of a continuous biochemical reactor in which cell reproduction is by mitosis. The uniqueness of steady-state operating points and the stability of these points are investigated. The system operated with a biomass-clear feed, a biomass-laden feed, and sinusoidally varying feed and effluent flow rates is analyzed. These modes of operation are suggested by commercial operation of sewage treatment facilities, as well as other continuous biochemical systems. Of these different ways of operating the reactor a biomass-laden feed and steady flow rates are required for a unique steady state operating point to exist. In all cases the system stability is governed by the nature of the specific death function describing the age-dependent probability of mitosis occurring.
AB - In this study we examine the operation of a continuous biochemical reactor in which cell reproduction is by mitosis. The uniqueness of steady-state operating points and the stability of these points are investigated. The system operated with a biomass-clear feed, a biomass-laden feed, and sinusoidally varying feed and effluent flow rates is analyzed. These modes of operation are suggested by commercial operation of sewage treatment facilities, as well as other continuous biochemical systems. Of these different ways of operating the reactor a biomass-laden feed and steady flow rates are required for a unique steady state operating point to exist. In all cases the system stability is governed by the nature of the specific death function describing the age-dependent probability of mitosis occurring.
UR - http://www.scopus.com/inward/record.url?scp=0019411761&partnerID=8YFLogxK
U2 - 10.1016/0022-5193(81)90314-3
DO - 10.1016/0022-5193(81)90314-3
M3 - 期刊論文
AN - SCOPUS:0019411761
SN - 0022-5193
VL - 89
SP - 321
EP - 333
JO - Journal of Theoretical Biology
JF - Journal of Theoretical Biology
IS - 2
ER -