Template-free synthesis of nanoporous gadolinium phosphonate as a magnetic resonance imaging (MRI) agent

Malay Pramanik; Fa Kuen Shieh; Saad M. Alshehri; Zeid Abdullah Alothman; Kevin C.W. Wu; Yusuke Yamauchi

doi:10.1039/c5ra02004b

Template-free synthesis of nanoporous gadolinium phosphonate as a magnetic resonance imaging (MRI) agent

Malay Pramanik, Fa Kuen Shieh, Saad M. Alshehri, Zeid Abdullah Alothman, Kevin C.W. Wu, Yusuke Yamauchi

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

A new series of organic-inorganic hybrid porous gadolinium phosphonate (GdP) materials have been synthesized using benzene-1,3,5-triphosphonic acid as a phosphonic acid linker through a simple hydrothermal technique. The particle size and morphology are well controlled through the selection of suitable reaction conditions. The obtained materials exhibit very high specific surface area and crystalline pore walls with a triclinic structure having unit cell parameters a = 7.76 (3) Å; b = 8.60 (6) Å; c = 14.09 (7) Å; α = 100.08 (4)°; β = 84.23 (6)°; γ = 116.29 (6)°. The obtained GdP materials are further used as a magnetic resonance imaging (MRI) contrast agent with r₁ and r₂ values of 2.6 and 4.7 s^-1 mM^-1, respectively.

Original language	English
Pages (from-to)	42762-42767
Number of pages	6
Journal	RSC Advances
Volume	5
Issue number	53
DOIs	https://doi.org/10.1039/c5ra02004b
State	Published - 2015

Access to Document

10.1039/c5ra02004b

Cite this

@article{530958e7cc4847559d06cc2df116e745,

title = "Template-free synthesis of nanoporous gadolinium phosphonate as a magnetic resonance imaging (MRI) agent",

abstract = "A new series of organic-inorganic hybrid porous gadolinium phosphonate (GdP) materials have been synthesized using benzene-1,3,5-triphosphonic acid as a phosphonic acid linker through a simple hydrothermal technique. The particle size and morphology are well controlled through the selection of suitable reaction conditions. The obtained materials exhibit very high specific surface area and crystalline pore walls with a triclinic structure having unit cell parameters a = 7.76 (3) {\AA}; b = 8.60 (6) {\AA}; c = 14.09 (7) {\AA}; α = 100.08 (4)°; β = 84.23 (6)°; γ = 116.29 (6)°. The obtained GdP materials are further used as a magnetic resonance imaging (MRI) contrast agent with r1 and r2 values of 2.6 and 4.7 s-1 mM-1, respectively.",

author = "Malay Pramanik and Shieh, {Fa Kuen} and Alshehri, {Saad M.} and Alothman, {Zeid Abdullah} and Wu, {Kevin C.W.} and Yusuke Yamauchi",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2015.",

year = "2015",

doi = "10.1039/c5ra02004b",

language = "???core.languages.en_GB???",

volume = "5",

pages = "42762--42767",

journal = "RSC Advances",

issn = "2046-2069",

number = "53",

}

TY - JOUR

T1 - Template-free synthesis of nanoporous gadolinium phosphonate as a magnetic resonance imaging (MRI) agent

AU - Pramanik, Malay

AU - Shieh, Fa Kuen

AU - Alshehri, Saad M.

AU - Alothman, Zeid Abdullah

AU - Wu, Kevin C.W.

AU - Yamauchi, Yusuke

N1 - Publisher Copyright: © The Royal Society of Chemistry 2015.

PY - 2015

Y1 - 2015

N2 - A new series of organic-inorganic hybrid porous gadolinium phosphonate (GdP) materials have been synthesized using benzene-1,3,5-triphosphonic acid as a phosphonic acid linker through a simple hydrothermal technique. The particle size and morphology are well controlled through the selection of suitable reaction conditions. The obtained materials exhibit very high specific surface area and crystalline pore walls with a triclinic structure having unit cell parameters a = 7.76 (3) Å; b = 8.60 (6) Å; c = 14.09 (7) Å; α = 100.08 (4)°; β = 84.23 (6)°; γ = 116.29 (6)°. The obtained GdP materials are further used as a magnetic resonance imaging (MRI) contrast agent with r1 and r2 values of 2.6 and 4.7 s-1 mM-1, respectively.

AB - A new series of organic-inorganic hybrid porous gadolinium phosphonate (GdP) materials have been synthesized using benzene-1,3,5-triphosphonic acid as a phosphonic acid linker through a simple hydrothermal technique. The particle size and morphology are well controlled through the selection of suitable reaction conditions. The obtained materials exhibit very high specific surface area and crystalline pore walls with a triclinic structure having unit cell parameters a = 7.76 (3) Å; b = 8.60 (6) Å; c = 14.09 (7) Å; α = 100.08 (4)°; β = 84.23 (6)°; γ = 116.29 (6)°. The obtained GdP materials are further used as a magnetic resonance imaging (MRI) contrast agent with r1 and r2 values of 2.6 and 4.7 s-1 mM-1, respectively.

UR - http://www.scopus.com/inward/record.url?scp=84929324926&partnerID=8YFLogxK

U2 - 10.1039/c5ra02004b

DO - 10.1039/c5ra02004b

M3 - 期刊論文

AN - SCOPUS:84929324926

SN - 2046-2069

VL - 5

SP - 42762

EP - 42767

JO - RSC Advances

JF - RSC Advances

IS - 53

ER -

Template-free synthesis of nanoporous gadolinium phosphonate as a magnetic resonance imaging (MRI) agent

Abstract

Access to Document

Fingerprint

Cite this