Surface-modified Polysulfone Hollow Fibers with Hydrophilic Group Having Improved Haemocompatibility

A. Higuchi, H. Hashiba, K. Shirano, R. Hayashi, B. O. Yoon

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


The polymerization of vinylpyrrolidone (PVP) or zwitter-ionic sulfoalkylbetaine (SPE) on the surface of the polysulfone (PSf) hollow fibers was investigated. It was found that the membranes used for chemical modification were PSf hollow fibers or ultrafiltration membranes having molecular weight cut-off of 6000. The results suggested that the hydrophilic surface of surface-modified PSf membranes suppressed platelet adhesion to PSf membranes. The results show that the PVP, SPE and aspartic acid (ASP) immobilized on the surface-modified PSf membranes contributed to the hydrophilic and haemocompatible sites on the surface of the PSf membranes.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
StatePublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 17 May 200421 May 2004

Publication series

NameTransactions - 7th World Biomaterials Congress


ConferenceTransactions - 7th World Biomaterials Congress


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