Solvent pulse desorption on-line solid-phase extraction combined with high-performance liquid chromatographic determination of 14 sulfonamides in environmental water samples

Yu Chieh Wang, Feng Chun Hsieh, Jia Lin Wang, Youn Yuen Shu

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

In this research study, we developed a convenient method for detecting the residue of sulfonamides in water samples using a manual injection valve, octyl (C8) as the sorbent in a solid-phase extraction column, high-performance liquid chromatography, and a diode array detector. Use of gradient flow for a solvent pulse can prevent the use of a second pump and a switch valve. This reduces the cost of instruments. Under optimal conditions, the limits of detection ranged from 0.54 to 3.67 μg L-1, and most drugs had a good relationship (R2 > 0.995). Moreover, during method validation, relative standard deviations for interday and intraday precision ranging from 0.3% to 12% and from 0.1% to 5.4%, respectively, were observed. This method was used to detect sulfonamide residues in environmental water, and the results indicate that neither of the two rivers we studied contained sulfonamides.

Original languageEnglish
Pages (from-to)4370-4375
Number of pages6
JournalAnalytical Methods
Volume11
Issue number34
DOIs
StatePublished - 14 Sep 2019

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