Simulated body-fluid tests and electrochemical investigations on biocompatibility of metallic glasses

C. H. Lin, C. H. Huang, J. F. Chuang, H. C. Lee, M. C. Liu, X. H. Du, J. C. Huang, J. S.C. Jang, C. H. Chen

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

This paper presents the in-vitro and electrochemical investigations of four metallic glasses (MGs) for finding potential MG-based bio-materials. The simulation body-fluid Hanks solution is utilized for testing the corrosion resistance of MGs, and microorganisms of Escherichia coli are used in testing the bio-toxicity. In addition, a simple cyclic voltammetry method is used for rapid verification of the potential electrochemical responses. It is found that the Zr-based MG can sustain in the body-fluid, exhibiting the best corrosion resistance and electrochemical stability. The microbiologic test shows that E. coli can grow on the surface of the Zr-based metallic glass, confirming the low cell toxicity of this Zr-based MG.

Original languageEnglish
Pages (from-to)2578-2582
Number of pages5
JournalMaterials Science and Engineering C
Volume32
Issue number8
DOIs
StatePublished - 1 Dec 2012

Keywords

  • Bio-toxicity
  • Corrosion resistance
  • Electrochemical stability
  • Metallic glasses
  • Simulation body-fluid

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