Simplified derivatization method for triclosan determination in personal care products by gas chromatography-mass spectrometry

Chiao Yin Cheng, Yu Chen Wang, Hsin Chang Chen, Wang Hsien Ding

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

An efficient and eco-friendly injection-port tert-butyldimethylsilylated (TBDMS) derivatization and gas chromatography-mass spectrometry (GC-MS) was developed to determine triclosan (TCS, an antibacterial agent) in the samples of toothpaste, liquid hand-soap and facial cleansing cream. This on-line derivatization coupled ultrasonic extraction provides sensitivity, fast and reproducible results for TCS analysis. The accuracy and precision of the method was evaluated. The developed method was successfully applied to determine the content of TCS in selected personal care products.

Original languageEnglish
Pages (from-to)49-52
Number of pages4
JournalJournal of the Chinese Chemical Society
Volume58
Issue number1
DOIs
StatePublished - Feb 2011

Keywords

  • GC-MS
  • Injection-port derivatization
  • Personal care products analysis
  • Triclosan

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