S-adenosyl-L-methionine-dependent methyl transfer: Observable precatalytic intermediates during DNA cytosine methylation

Medicine & Life Sciences

• Adenosine 9%
• Anti-Bacterial Agents 6%
• Catalytic DNA 14%
• Catalytic Domain 43%
• Cytosine 69%
• DNA 16%
• DNA Methylation 57%
• Enzymes 10%
• Hydrogen Bonding 34%
• Hydrolysis 8%
• Kinetics 14%
• Mechanics 20%
• Methionine 10%
• Methylation 8%
• Methyltransferases 10%
• Molecular Dynamics Simulation 10%
• Mutation 5%
• Neoplasms 3%
• Observation 6%
• Pharmaceutical Preparations 4%
• Proteins 3%
• pyrimidine 11%
• S-Adenosylmethionine 76%
• Water 12%

Chemical Compounds

• Adenosine 27%
• Antimicrobial Agent 20%
• Cofactor 26%
• Cytosine 30%
• DNA Cytosine 100%
• Drug Target 33%
• Hydrolysis 17%
• Methionine 29%
• Molecular Dynamics 21%
• Molecular Mechanic 28%
• Mutation 24%
• Nucleophile 25%
• Protein 11%
• Pyrimidine 25%
• Quantum Mechanics 33%