Reduction of 1-pyrrolyl and 1-indolyl carbamates to hemiaminals

He Chu Hsu, Duen Ren Hou

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Hemiaminals of pyrroles and indoles have been prepared from the lithium aluminum hydride reduction of 1-pyrrolyl and 1-indolyl carbamates with good yields (67-82%). These carbamates are more reactive than aliphatic amides and carbamates under the LAH reduction, but less reactive than esters.

Original languageEnglish
Pages (from-to)7169-7171
Number of pages3
JournalTetrahedron Letters
Volume50
Issue number51
DOIs
StatePublished - 23 Dec 2009

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