Real-time monitoring on peptide synthesis by GMR biosensors

Jiann Hwa Lue, Ting Jou Ding, Tsung Hsun Yang, Jenq Yang Chang, Wen Yih Chen

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

In this work, a real-time monitoring system has been developed. The micro-optic device applying the guided-mode resonance (GMR) effect has been designed and fabricated. By combining a simple and low cost microfluidic channel, the GMR measurement for detecting peptide synthesis reaction has been explored. It is able to determine whether or not the chemical reaction reacts and how far the chemical reaction arrived. In addition, the kinetics analysis for the peptide synthesis has also been discussed. It is successfully demonstrated that the GMR device is capable of monitoring the process of peptide synthesis in real time.

Original languageEnglish
Title of host publicationProceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011
Pages1858-1861
Number of pages4
DOIs
StatePublished - 2011
Event2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011 - Shanghai, China
Duration: 15 Oct 201117 Oct 2011

Publication series

NameProceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011
Volume4

Conference

Conference2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011
Country/TerritoryChina
CityShanghai
Period15/10/1117/10/11

Keywords

  • guided-mode resonance
  • kinetics analysis
  • peptide synthesis
  • real-time monitoring system
  • waveguide

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